检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2015年
2期
177-178,181
,共3页
ED T A依赖性假性血小板减少症%肝素锂%枸橼酸钠
ED T A依賴性假性血小闆減少癥%肝素鋰%枸櫞痠鈉
ED T A의뢰성가성혈소판감소증%간소리%구연산납
EDTA-dependent PTCP%heparin lithium%sodium citrate
目的：乙二胺四乙酸（EDTA）依赖性假性血小板减少症标本通过肝素锂、枸橼酸钠及改良方案进行纠正，对血小板测定结果进行评估，建立一个简单、实用、且不延长结果报告时间（TAT）的方法。方法征集ED‐TA依赖性假性血小板减少症志愿者120例，同时收集肝素锂、枸橼酸钠、EDTA‐K3抗凝标本各一份，其中EDTA‐K3标本采用改良方法处理后再检测，三组检测结果与参考方法的测定结果进行比较。评估差异有无统计学意义。结果肝素锂、枸橼酸钠、改良方案的纠正率分别为80．5％、39．2％、100．0％；与参考方法比较，P值分别0．129、0．013、0．051。T A T分别为（2．03±0．29）、（1．8±0．35）、（0．47±0．19）h。结论肝素锂组的结果与参考方法测定结果相关性最好，可比性最好。其次是改良组和枸橼酸钠组。改良方案对 TAT影响最小、不用进行患者的二次采血，并且结果与枸橼酸钠相似，因此该改良方案可以用于临床上对PTCP标本的纠正。
目的：乙二胺四乙痠（EDTA）依賴性假性血小闆減少癥標本通過肝素鋰、枸櫞痠鈉及改良方案進行糾正，對血小闆測定結果進行評估，建立一箇簡單、實用、且不延長結果報告時間（TAT）的方法。方法徵集ED‐TA依賴性假性血小闆減少癥誌願者120例，同時收集肝素鋰、枸櫞痠鈉、EDTA‐K3抗凝標本各一份，其中EDTA‐K3標本採用改良方法處理後再檢測，三組檢測結果與參攷方法的測定結果進行比較。評估差異有無統計學意義。結果肝素鋰、枸櫞痠鈉、改良方案的糾正率分彆為80．5％、39．2％、100．0％；與參攷方法比較，P值分彆0．129、0．013、0．051。T A T分彆為（2．03±0．29）、（1．8±0．35）、（0．47±0．19）h。結論肝素鋰組的結果與參攷方法測定結果相關性最好，可比性最好。其次是改良組和枸櫞痠鈉組。改良方案對 TAT影響最小、不用進行患者的二次採血，併且結果與枸櫞痠鈉相似，因此該改良方案可以用于臨床上對PTCP標本的糾正。
목적：을이알사을산（EDTA）의뢰성가성혈소판감소증표본통과간소리、구연산납급개량방안진행규정，대혈소판측정결과진행평고，건립일개간단、실용、차불연장결과보고시간（TAT）적방법。방법정집ED‐TA의뢰성가성혈소판감소증지원자120례，동시수집간소리、구연산납、EDTA‐K3항응표본각일빈，기중EDTA‐K3표본채용개량방법처리후재검측，삼조검측결과여삼고방법적측정결과진행비교。평고차이유무통계학의의。결과간소리、구연산납、개량방안적규정솔분별위80．5％、39．2％、100．0％；여삼고방법비교，P치분별0．129、0．013、0．051。T A T분별위（2．03±0．29）、（1．8±0．35）、（0．47±0．19）h。결론간소리조적결과여삼고방법측정결과상관성최호，가비성최호。기차시개량조화구연산납조。개량방안대 TAT영향최소、불용진행환자적이차채혈，병차결과여구연산납상사，인차해개량방안가이용우림상상대PTCP표본적규정。
Objective To correct the specimens of EDTA‐dependent pseudothrombocytopenia(PTCT ) by a‐dopting heparin lithium ,sodium sitrate and the improved corrective solution and to evaluate the platelet detection re‐sults for establishing a simple ,practical method without extending the results report time .Methods 120 volunteer of EDTA‐dependent PTCT and each anti‐coagulation specimen with EDTA‐K3 ,heparin lithium and sodium citrate were collected ,in which the specimens of EDTA‐K3 was treated by the improved method and then the detection was con‐ducted .The detection results in 3 groups were compared with the detection results by the reference method and whether having the statistical significance was evaluated .Results The corrective rates of heparin lithium ,sodium cit‐rate and improved corrective solution were 80 .5% ,39 .2% and 100 .0% .Their P values were 0 .129 ,0 .013 and 0 .051 respectively .Their result report time(TAT) were(2 .03 ± 0 .29) ,(1 .8 ± 0 .35) ,(0 .47 ± 0 .19) h respectively .Conclu‐sion The results of the heparin lithium group has the best correlation and the detection results by the reference method and the best comparability ,followed by the improved group and the sodium citrate group .The improved cor‐rective scheme has the minimal influence on TAT and without needing to collect blood specimen twice ,its detection results are close to those detected by the sodium citrate method .Therefore the improved corrective scheme can be used to correct the PTCP specimens in clinic .
