CAJ | 학술논문

目的：探讨眼眶朗格汉斯细胞组织细胞增生症(LCH)的 MRI 表现特征,提高其诊断准确性。方法回顾性分析经术后病理证实的14例眼眶 LCH 患者的临床及 MRI 资料。结果9例患者以眼睑肿胀或伴炎症表现、眼突、眼部肿物就诊,本组中1例伴有明显咳嗽、咳痰,1例伴有多饮多尿症状。右眶病变7例,左眶病变6例,双眶同时受累1例。外上壁交界处病灶6例,外侧壁病变5例,上壁病变3例。MRI 表现：13例 T1 WI 上呈等、低信号,11例 T2 WI 上呈不均匀等、高信号,多数信号不均匀。嗜酸性肉芽肿病灶边界较清楚,其他类型多边界不清。增强后病变多数呈较明显不均匀强化。结论MRI 可清楚、准确地显示 LCH 病变范围,结合临床表现有助于本病早期诊断,MRI 可为临床制订手术方案、治疗计划提供可靠依据。
목적：탐토안광랑격한사세포조직세포증생증(LCH)적 MRI 표현특정,제고기진단준학성。방법회고성분석경술후병리증실적14례안광 LCH 환자적림상급 MRI 자료。결과9례환자이안검종창혹반염증표현、안돌、안부종물취진,본조중1례반유명현해수、해담,1례반유다음다뇨증상。우광병변7례,좌광병변6례,쌍광동시수루1례。외상벽교계처병조6례,외측벽병변5례,상벽병변3례。MRI 표현：13례 T1 WI 상정등、저신호,11례 T2 WI 상정불균균등、고신호,다수신호불균균。기산성육아종병조변계교청초,기타류형다변계불청。증강후병변다수정교명현불균균강화。결론MRI 가청초、준학지현시 LCH 병변범위,결합림상표현유조우본병조기진단,MRI 가위림상제정수술방안、치료계화제공가고의거。
Objective To investigate diagnostic magnetic resonance imaging features of orbital Langerhans cell histocytosis (LCH)and improve its diagnostic accuracy.Methods The symptoms and image data of fourteen histophathology verified orbital LCH cases are reviewed and analyzed.Results Nine patients had swollen eyelids,accompanying with symptoms of inflammation, esphthalmos and orbital masses.One case had cough symptom and another had diabetes insipidus.Of these fourteen cases,seven occurred in right orbital,six occurred in left orbital and one involved bilateral orbital.As to the location of LCH,six cases located in super-lateral wall of the orbit,five cases located in lateral wall of the orbital,and three cases located in roof of orbital.On MRI, thirteen cases lesions show hypo or iso signal intensity on T1 WI,and eleven cases lesions show heterogeneous hyper or iso signal in-tensity on T2 WI.The lesions of eosinophilic granuloma has clear border,which differentiate it from other types.After contrast en-hancement,MR imaging showed marked inhomogeneous enhancement.Conclusion MRI is the primary modality in diagnosing of or-bital LCH,clearly and accurately manifesting the extent of orbital LCH.It will be helpful to diagnose LCH timely if combining with clinical data.MR could provide reliable information for making surgical operation and treatment plan.