CAJ | 학술논문

重叠综合征治疗的重点在于2种疾病中每个疾病治疗效果最大化，其客观目标包括纠正患者的睡眠片段化、降低住院率与病死率，主观目标在于改善患者机体功能、睡眠及生活质量。目前重叠综合征患者主要依靠气道正压通气治疗，维持通气量改善换气功能。氧疗作为辅助通气治疗措施能够缓解低氧状态。药物治疗的关键在于扩张支气管，清除分泌物，降低炎症反应以改善通气功能。同时，日常活动锻炼及生活饮食习惯在其疾病的治疗措施中不可或缺，对改善患者的运动功能及提高生活质量有重要的辅助作用。
중첩종합정치료적중점재우2충질병중매개질병치료효과최대화，기객관목표포괄규정환자적수면편단화、강저주원솔여병사솔，주관목표재우개선환자궤체공능、수면급생활질량。목전중첩종합정환자주요의고기도정압통기치료，유지통기량개선환기공능。양료작위보조통기치료조시능구완해저양상태。약물치료적관건재우확장지기관，청제분비물，강저염증반응이개선통기공능。동시，일상활동단련급생활음식습관재기질병적치료조시중불가혹결，대개선환자적운동공능급제고생활질량유중요적보조작용。
The key treatment for overlap syndrome should focus on maximizing the therapeutic effect of each condition and concentrate of interventions that have showed benefit in both diseases. The goal of therapy includes the improvement in objective data including the reduction in sleep fragmentation, exacerbation rate, hospitalization frequency and mortality, and subjective data such as daytime functioning, quality of life and sleep quality. At present, the treatment of overlap syndrome is mainly rely on the positive airway pressure to improve ventilatory capacity and gas exchange function. Oxygen therapy as auxiliary treatment can alleviate hypoxemia. The key of drug therapy is to dilate the bronchus, clear secretions, reduce in?flammatory response to improve the ventilation function. Meanwhile, daily exercise and dietary habits of life activity are indis?pensable in the treatment of the disease as important supporting role to improve the motor function and the quality of life in patients.