CAJ | 학술논문

目的：对比分析应用超选择性动脉溶栓与静脉溶栓治疗急性脑梗死的临床疗效和可靠性。方法按照数字表法将2013年4月～2014年4月我院148例应用尿激酶溶栓治疗的急性脑梗死患者分成对照组（静脉溶栓）和观察组（超选择性动脉溶栓）各74例，对两组患者治疗后1个月的临床显效率以及NIHSS评分进行比较。结果观察组治疗后的临床总有效率86.49%，对照组治疗后的临床总有效率68.92%，两组比较差异具有统计学意义（P＜0.05）；观察组治疗后30 min、12 h、1 d、7 d NIHSS评分均低于对照组，两组比较差异具有统计学意义（P＜0.05）。结论急性脑梗死患者应用尿激酶超选择性动脉溶栓治疗对NIHSS评分的改善以及临床的治疗效果均好于静脉溶栓治疗，临床应用安全可靠，具有临床推广应用价值。
목적：대비분석응용초선택성동맥용전여정맥용전치료급성뇌경사적림상료효화가고성。방법안조수자표법장2013년4월～2014년4월아원148례응용뇨격매용전치료적급성뇌경사환자분성대조조（정맥용전）화관찰조（초선택성동맥용전）각74례，대량조환자치료후1개월적림상현효솔이급NIHSS평분진행비교。결과관찰조치료후적림상총유효솔86.49%，대조조치료후적림상총유효솔68.92%，량조비교차이구유통계학의의（P＜0.05）；관찰조치료후30 min、12 h、1 d、7 d NIHSS평분균저우대조조，량조비교차이구유통계학의의（P＜0.05）。결론급성뇌경사환자응용뇨격매초선택성동맥용전치료대NIHSS평분적개선이급림상적치료효과균호우정맥용전치료，림상응용안전가고，구유림상추엄응용개치。
Objective To comparison and Evaluation the clinical curative effect and reliability security of supperselected intraaterial thrombolysis and venous thrombolysis in treating acute cerebral infarction. Methods According to the digital meter method,148 cases patients with acute cerebral infarction were divided into observation groups(supperselected intraaterial thrombolysis) and control groups(venous thrombolysis),each group has 74 cases. to compare the total effective rate and the NIHSS score after treatment.Results The total effective rate of control group was 68.92%after one month treatment, The total effective rate of observation group was 86.49% after one month treatment, the difference between two group was significant (P<0.05);The NIHSS score of the observation group was lower than control group after their treatment in 30 min、12 h、1 d、、7 d later,the difference between two group was significant(P<0.05). Conclusion The improve of NIHSS score and the clinical curative effect of supperselected intraaterial thrombolysis was better than that of venous thrombolysis with urokinase.It has the value of clinical application.