郑州大学学报(医学版)
鄭州大學學報(醫學版)
정주대학학보(의학판)
JOURNAL OF ZHENGZHOU UNIVERSITY(MEDICAL SCIENCES)
2015年
1期
138-141
,共4页
陈玉凤%郭献山%王林栋%赵建林%耿秀琴%张威
陳玉鳳%郭獻山%王林棟%趙建林%耿秀琴%張威
진옥봉%곽헌산%왕림동%조건림%경수금%장위
2型糖尿病%非创伤性骨折%糖尿病周围神经病变%骨密度%危险因素
2型糖尿病%非創傷性骨摺%糖尿病週圍神經病變%骨密度%危險因素
2형당뇨병%비창상성골절%당뇨병주위신경병변%골밀도%위험인소
type 2 diabetes mellitus%non-traumatic fracture%diabetic peripheral neuropathy%bone mineral density%risk factor
目的:探讨糖尿病合并非创伤性骨折患者的骨折部位和相关危险因素。方法:147例2型糖尿病患者分为非创伤性骨折组(骨折组)72例和无骨折组(对照组)75例。比较两组患者的年龄、性别、体重指数、病程、空腹血糖、糖化血红蛋白、血糖控制方法、中风及心脏病史、既往骨折病情况,糖尿病视网膜病变、糖尿病周围神经病变、骨密度( BMD)。采用logistic回归分析方法分析非创伤性骨折的危险因素。结果:72例骨折病例中,髋部是最常见的骨折部位(31.6%)。骨折组患者伴有糖尿病视网膜病变、糖尿病周围神经病变、中风病史、既往骨折病史的发生率高于对照组(χ2=4.461、16.642、4.140、7.771,P<0.05),BMD低于对照组(t=4.452,P=0.037)。 Logistic回归分析结果提示既往骨折病史和糖尿病周围神经病变是骨折的独立危险因素( OR=3.800、10.419,95%CI=1.180~12.237、3.727~29.132)。结论:糖尿病合并非创伤性骨折中髋部骨折发生率最高,既往骨折病史和糖尿病周围神经病变是其发生的危险因素。
目的:探討糖尿病閤併非創傷性骨摺患者的骨摺部位和相關危險因素。方法:147例2型糖尿病患者分為非創傷性骨摺組(骨摺組)72例和無骨摺組(對照組)75例。比較兩組患者的年齡、性彆、體重指數、病程、空腹血糖、糖化血紅蛋白、血糖控製方法、中風及心髒病史、既往骨摺病情況,糖尿病視網膜病變、糖尿病週圍神經病變、骨密度( BMD)。採用logistic迴歸分析方法分析非創傷性骨摺的危險因素。結果:72例骨摺病例中,髖部是最常見的骨摺部位(31.6%)。骨摺組患者伴有糖尿病視網膜病變、糖尿病週圍神經病變、中風病史、既往骨摺病史的髮生率高于對照組(χ2=4.461、16.642、4.140、7.771,P<0.05),BMD低于對照組(t=4.452,P=0.037)。 Logistic迴歸分析結果提示既往骨摺病史和糖尿病週圍神經病變是骨摺的獨立危險因素( OR=3.800、10.419,95%CI=1.180~12.237、3.727~29.132)。結論:糖尿病閤併非創傷性骨摺中髖部骨摺髮生率最高,既往骨摺病史和糖尿病週圍神經病變是其髮生的危險因素。
목적:탐토당뇨병합병비창상성골절환자적골절부위화상관위험인소。방법:147례2형당뇨병환자분위비창상성골절조(골절조)72례화무골절조(대조조)75례。비교량조환자적년령、성별、체중지수、병정、공복혈당、당화혈홍단백、혈당공제방법、중풍급심장병사、기왕골절병정황,당뇨병시망막병변、당뇨병주위신경병변、골밀도( BMD)。채용logistic회귀분석방법분석비창상성골절적위험인소。결과:72례골절병례중,관부시최상견적골절부위(31.6%)。골절조환자반유당뇨병시망막병변、당뇨병주위신경병변、중풍병사、기왕골절병사적발생솔고우대조조(χ2=4.461、16.642、4.140、7.771,P<0.05),BMD저우대조조(t=4.452,P=0.037)。 Logistic회귀분석결과제시기왕골절병사화당뇨병주위신경병변시골절적독립위험인소( OR=3.800、10.419,95%CI=1.180~12.237、3.727~29.132)。결론:당뇨병합병비창상성골절중관부골절발생솔최고,기왕골절병사화당뇨병주위신경병변시기발생적위험인소。
Aim:To evaluate risk factors for non-traumatic fracture and the fracture site in patients with diabetes mel-litus.Methods:A total of 147 patients with type 2 mellitus diabetes were divided into two groups: non-traumatic fracture group (fracture group,72 cases) and non-fracture group(control group,75 cases).Age, gender, body mass index, dura-tion of diabetes, fasting glucose, glycated hemoglobin, glycemic control methods, stroke, heart disease, and fracture histo-ry, diabetic retinopathy ,diabetic peripheral neuropathy , and bone mineral density ( BMD) were compared between the two groups.The risk factors for non-traumatic fractures was analyzed by logistic regression analysis .Results:The hip was the most frequent fracture site(31.6%) in fracture group.Diabetic retinopathy, diabetic peripheral neuropathy , and history of stroke and fractures were more common in fracture group than in control group (χ2 =4.461,16.642,4.140,7.771,P<0.05).Fracture group had lower BMD(t=4.452,P=0.037).Logistic regression analysis showed that history of fracture and diabetic peripheral neuropathy were independent risk factors for non -traumatic fracture(OR=3.800,10.419,95%CI=1.180-12.237,3.727-29.132).Conclusion:Hip fracture is the most common fracture in type 2 diabetes mellitus with non-traumatic fractures .Diabetic peripheral neuropathy is closely related to fracture .