临床口腔医学杂志
臨床口腔醫學雜誌
림상구강의학잡지
JOURNAL OF CLINICAL STOMATOLOGY
2015年
1期
43-45
,共3页
CPP-ACP%五倍子%早期釉质龋
CPP-ACP%五倍子%早期釉質齲
CPP-ACP%오배자%조기유질우
CPP-ACP%Galla Chinensis%Early enamel caries
目的：比较酪蛋白磷酸多肽钙磷复合体（CPP－ACP）和五倍子提取物对早期釉质龋保守治疗的临床疗效。方法：选择早期牙釉质龋患牙315颗，随机分为3组：CPP－ACP组105颗牙，治疗药物为CPP－ACP糊剂；五倍子组108颗牙，治疗药物为1 mg／mL五倍子提取溶液；对照组102颗牙，采用蒸馏水做空白对照，涂药前病损区域用酒精处理、干棉球隔湿，清洁牙齿后将药物均匀涂抹于病损处，5 min后棉球擦拭，30 min内避免饮水和进食，3组药物使用频率为2次／d×90 d，30 d复诊1次，连续使用12个月后观察治疗有效率和龋病控制率。结果：CPP－ACP组治疗有效率94．29％，龋病控制率98．09％，五倍子组治疗有效率83．33％，龋病控制率97．22％，对照组组治疗有效率0．98％，龋病控制率51．96％。经统计学处理，两种治疗方法的有效率与空白对照组的差别均有统计学意义（P＜0．05），CPP－ACP组与五倍子组的组间差异有统计学意义（P＜0．05），CPP－ACP组治疗有效率高于五倍子组；两种治疗方法的龋病控制率与空白对照组的差别均有统计学意义（P＜0．05），CPP－ACP组与五倍子组的组间差异没有统计学意义（P＞0．05）。结论：CPP－ACP和五倍子提取物局部应用可有效控制早期牙釉质龋，但前者临床治疗效果更为显著。
目的：比較酪蛋白燐痠多肽鈣燐複閤體（CPP－ACP）和五倍子提取物對早期釉質齲保守治療的臨床療效。方法：選擇早期牙釉質齲患牙315顆，隨機分為3組：CPP－ACP組105顆牙，治療藥物為CPP－ACP糊劑；五倍子組108顆牙，治療藥物為1 mg／mL五倍子提取溶液；對照組102顆牙，採用蒸餾水做空白對照，塗藥前病損區域用酒精處理、榦棉毬隔濕，清潔牙齒後將藥物均勻塗抹于病損處，5 min後棉毬抆拭，30 min內避免飲水和進食，3組藥物使用頻率為2次／d×90 d，30 d複診1次，連續使用12箇月後觀察治療有效率和齲病控製率。結果：CPP－ACP組治療有效率94．29％，齲病控製率98．09％，五倍子組治療有效率83．33％，齲病控製率97．22％，對照組組治療有效率0．98％，齲病控製率51．96％。經統計學處理，兩種治療方法的有效率與空白對照組的差彆均有統計學意義（P＜0．05），CPP－ACP組與五倍子組的組間差異有統計學意義（P＜0．05），CPP－ACP組治療有效率高于五倍子組；兩種治療方法的齲病控製率與空白對照組的差彆均有統計學意義（P＜0．05），CPP－ACP組與五倍子組的組間差異沒有統計學意義（P＞0．05）。結論：CPP－ACP和五倍子提取物跼部應用可有效控製早期牙釉質齲，但前者臨床治療效果更為顯著。
목적：비교락단백린산다태개린복합체（CPP－ACP）화오배자제취물대조기유질우보수치료적림상료효。방법：선택조기아유질우환아315과，수궤분위3조：CPP－ACP조105과아，치료약물위CPP－ACP호제；오배자조108과아，치료약물위1 mg／mL오배자제취용액；대조조102과아，채용증류수주공백대조，도약전병손구역용주정처리、간면구격습，청길아치후장약물균균도말우병손처，5 min후면구찰식，30 min내피면음수화진식，3조약물사용빈솔위2차／d×90 d，30 d복진1차，련속사용12개월후관찰치료유효솔화우병공제솔。결과：CPP－ACP조치료유효솔94．29％，우병공제솔98．09％，오배자조치료유효솔83．33％，우병공제솔97．22％，대조조조치료유효솔0．98％，우병공제솔51．96％。경통계학처리，량충치료방법적유효솔여공백대조조적차별균유통계학의의（P＜0．05），CPP－ACP조여오배자조적조간차이유통계학의의（P＜0．05），CPP－ACP조치료유효솔고우오배자조；량충치료방법적우병공제솔여공백대조조적차별균유통계학의의（P＜0．05），CPP－ACP조여오배자조적조간차이몰유통계학의의（P＞0．05）。결론：CPP－ACP화오배자제취물국부응용가유효공제조기아유질우，단전자림상치료효과경위현저。
Objective:To compare and study the clinical curative effect of casein phosphopeptides-amorphous calci-um phosphate (CPP-ACP) and galla chinensis extractive on early enamel caries. Method:315 cases of teeth with early enamel caries were enrolled and divided into three groups,and the specimens were randomly assigned to three groups:CPP-ACP group,galla chinensis group,and control group. The use of two drugs and distilled water were painted on lesion area af-ter alcohol treatment and dry cotton moisture barrier,5min later wipe with the cotton,avoid drinking and eating for 30 min, bid,return visit every month,and continues use for 3 months,To observe and compare the effective rate of treatment and con-trol rate of caries after 12 months. Result:The effective rate of treatment and control rate of CPP-ACP group is 94.29%and 98.09 %,Galla Chinensis group is 83.33 % and 97.22 %,the control group is 0.98% and 51.96 %.The effective treatment rate of CPP-ACP group and Galla Chinensis group was obviously higher than that in control group(P<0.05),and the former is higher than the later (P<0.05). The control rate of CPP-ACP group and Galla Chinensis group and showed no significant difference between the two groups (P>0.05). Conclusion:The local application of CPP-ACP and galla chinensis can effec-tively control the early enamel caries,but CPP-ACP's clinical treatment effect is more obvious.
