临床口腔医学杂志
臨床口腔醫學雜誌
림상구강의학잡지
JOURNAL OF CLINICAL STOMATOLOGY
2015年
1期
43-45
,共3页
CPP-ACP%五倍子%早期釉质龋
CPP-ACP%五倍子%早期釉質齲
CPP-ACP%오배자%조기유질우
CPP-ACP%Galla Chinensis%Early enamel caries
目的:比较酪蛋白磷酸多肽钙磷复合体(CPP-ACP)和五倍子提取物对早期釉质龋保守治疗的临床疗效。方法:选择早期牙釉质龋患牙315颗,随机分为3组:CPP-ACP组105颗牙,治疗药物为CPP-ACP糊剂;五倍子组108颗牙,治疗药物为1 mg/mL五倍子提取溶液;对照组102颗牙,采用蒸馏水做空白对照,涂药前病损区域用酒精处理、干棉球隔湿,清洁牙齿后将药物均匀涂抹于病损处,5 min后棉球擦拭,30 min内避免饮水和进食,3组药物使用频率为2次/d×90 d,30 d复诊1次,连续使用12个月后观察治疗有效率和龋病控制率。结果:CPP-ACP组治疗有效率94.29%,龋病控制率98.09%,五倍子组治疗有效率83.33%,龋病控制率97.22%,对照组组治疗有效率0.98%,龋病控制率51.96%。经统计学处理,两种治疗方法的有效率与空白对照组的差别均有统计学意义(P<0.05),CPP-ACP组与五倍子组的组间差异有统计学意义(P<0.05),CPP-ACP组治疗有效率高于五倍子组;两种治疗方法的龋病控制率与空白对照组的差别均有统计学意义(P<0.05),CPP-ACP组与五倍子组的组间差异没有统计学意义(P>0.05)。结论:CPP-ACP和五倍子提取物局部应用可有效控制早期牙釉质龋,但前者临床治疗效果更为显著。
目的:比較酪蛋白燐痠多肽鈣燐複閤體(CPP-ACP)和五倍子提取物對早期釉質齲保守治療的臨床療效。方法:選擇早期牙釉質齲患牙315顆,隨機分為3組:CPP-ACP組105顆牙,治療藥物為CPP-ACP糊劑;五倍子組108顆牙,治療藥物為1 mg/mL五倍子提取溶液;對照組102顆牙,採用蒸餾水做空白對照,塗藥前病損區域用酒精處理、榦棉毬隔濕,清潔牙齒後將藥物均勻塗抹于病損處,5 min後棉毬抆拭,30 min內避免飲水和進食,3組藥物使用頻率為2次/d×90 d,30 d複診1次,連續使用12箇月後觀察治療有效率和齲病控製率。結果:CPP-ACP組治療有效率94.29%,齲病控製率98.09%,五倍子組治療有效率83.33%,齲病控製率97.22%,對照組組治療有效率0.98%,齲病控製率51.96%。經統計學處理,兩種治療方法的有效率與空白對照組的差彆均有統計學意義(P<0.05),CPP-ACP組與五倍子組的組間差異有統計學意義(P<0.05),CPP-ACP組治療有效率高于五倍子組;兩種治療方法的齲病控製率與空白對照組的差彆均有統計學意義(P<0.05),CPP-ACP組與五倍子組的組間差異沒有統計學意義(P>0.05)。結論:CPP-ACP和五倍子提取物跼部應用可有效控製早期牙釉質齲,但前者臨床治療效果更為顯著。
목적:비교락단백린산다태개린복합체(CPP-ACP)화오배자제취물대조기유질우보수치료적림상료효。방법:선택조기아유질우환아315과,수궤분위3조:CPP-ACP조105과아,치료약물위CPP-ACP호제;오배자조108과아,치료약물위1 mg/mL오배자제취용액;대조조102과아,채용증류수주공백대조,도약전병손구역용주정처리、간면구격습,청길아치후장약물균균도말우병손처,5 min후면구찰식,30 min내피면음수화진식,3조약물사용빈솔위2차/d×90 d,30 d복진1차,련속사용12개월후관찰치료유효솔화우병공제솔。결과:CPP-ACP조치료유효솔94.29%,우병공제솔98.09%,오배자조치료유효솔83.33%,우병공제솔97.22%,대조조조치료유효솔0.98%,우병공제솔51.96%。경통계학처리,량충치료방법적유효솔여공백대조조적차별균유통계학의의(P<0.05),CPP-ACP조여오배자조적조간차이유통계학의의(P<0.05),CPP-ACP조치료유효솔고우오배자조;량충치료방법적우병공제솔여공백대조조적차별균유통계학의의(P<0.05),CPP-ACP조여오배자조적조간차이몰유통계학의의(P>0.05)。결론:CPP-ACP화오배자제취물국부응용가유효공제조기아유질우,단전자림상치료효과경위현저。
Objective:To compare and study the clinical curative effect of casein phosphopeptides-amorphous calci-um phosphate (CPP-ACP) and galla chinensis extractive on early enamel caries. Method:315 cases of teeth with early enamel caries were enrolled and divided into three groups,and the specimens were randomly assigned to three groups:CPP-ACP group,galla chinensis group,and control group. The use of two drugs and distilled water were painted on lesion area af-ter alcohol treatment and dry cotton moisture barrier,5min later wipe with the cotton,avoid drinking and eating for 30 min, bid,return visit every month,and continues use for 3 months,To observe and compare the effective rate of treatment and con-trol rate of caries after 12 months. Result:The effective rate of treatment and control rate of CPP-ACP group is 94.29%and 98.09 %,Galla Chinensis group is 83.33 % and 97.22 %,the control group is 0.98% and 51.96 %.The effective treatment rate of CPP-ACP group and Galla Chinensis group was obviously higher than that in control group(P<0.05),and the former is higher than the later (P<0.05). The control rate of CPP-ACP group and Galla Chinensis group and showed no significant difference between the two groups (P>0.05). Conclusion:The local application of CPP-ACP and galla chinensis can effec-tively control the early enamel caries,but CPP-ACP's clinical treatment effect is more obvious.