CAJ | 학술논문

目的：了解近年来南方医科大学附属深圳妇幼保健院收治的妊娠期高血压疾病患者的发病趋势、并发症情况及对妊娠结局的影响。方法回顾性分析2009年1月至2013年12月在南方医科大学附属深圳妇幼保健院就诊并分娩的2486例妊娠期高血压疾病患者的临床资料，包括发病率、孕妇年龄、住院天数、分娩方式、流动人口比例及母婴并发症等。结果5年间我院重度子痫前期发生率呈现下降趋势，从2009年的1．74％降至2013年的1．34％（X2＝12．321，P＜0．05）；流动人口所占比例较高（46．46％）；分娩方式仍然以剖宫产为主（74．09％），高于阴道分娩（21．44％），（X2＝736．084，P＜0．001）。妊娠期高血压疾病孕妇严重并发症的构成依次是：产后出血、胎盘早剥、HELLP综合征、心功能不全、弥散性血管内凝血、急性肾衰竭、脑血管意外；其围产儿严重并发症的构成依次为：早产、胎儿生长受限、新生儿窒息、死胎、流产。结论妊娠期高血压疾病仍是威胁孕产妇以及围产儿健康的严重疾病，必须加强产前保健，早发现、早诊断和早治疗，以改善母婴妊娠结局。
목적：료해근년래남방의과대학부속심수부유보건원수치적임신기고혈압질병환자적발병추세、병발증정황급대임신결국적영향。방법회고성분석2009년1월지2013년12월재남방의과대학부속심수부유보건원취진병분면적2486례임신기고혈압질병환자적림상자료，포괄발병솔、잉부년령、주원천수、분면방식、류동인구비례급모영병발증등。결과5년간아원중도자간전기발생솔정현하강추세，종2009년적1．74％강지2013년적1．34％（X2＝12．321，P＜0．05）；류동인구소점비례교고（46．46％）；분면방식잉연이부궁산위주（74．09％），고우음도분면（21．44％），（X2＝736．084，P＜0．001）。임신기고혈압질병잉부엄중병발증적구성의차시：산후출혈、태반조박、HELLP종합정、심공능불전、미산성혈관내응혈、급성신쇠갈、뇌혈관의외；기위산인엄중병발증적구성의차위：조산、태인생장수한、신생인질식、사태、유산。결론임신기고혈압질병잉시위협잉산부이급위산인건강적엄중질병，필수가강산전보건，조발현、조진단화조치료，이개선모영임신결국。
Objective To investigate the clinical incidence trend , complication and pregnancy outcome of hypertensive disorders in pregnancy of Shenzhen Maternity and Child Healthcare Hospital Affiliated to Southern Medical University in recent years .Methods A retrospective study was conducted in 2 486 patients with hypertensive disorders in pregnancy , who were admitted in Shenzhen Maternity and Child Healthcare Hospital Affiliated to Southern Medical University from January 2009 to December 2013. The clinical data included morbidity , maternal age , days of hospitalization , delivery mode , the proportion of floating population, and the maternal and infant complications .Results During 5 years,the incidence rate of severe preeclampsia decreased from 1.74%(in 2009) to 1.34%(in 2013), ( X2 =12.321, P<0.05).The proportion of floating population was quit high (46.46%).The incidence rate of cesarean section (74.01%) was higher than that of vaginal delivery (21.44%), ( X2 =736.084, P<0.001).The ratio of the serious complicationsby hypertensive disorders in pregnancy was postpartum hemorrhage , placental abruption , HELLP syndrome , heart failure , disseminated intravascular coagulation , acute renal failure, and cerebrovascular accident .The ratio of perinatal serious complications was preterm birth , fetal growth restriction, neonatal asphyxia, stillbirth, and abortion.Conclusions Hypertensive disorders in pregnancy is still threating to maternal and perinatal health .The perinatal outcome can be improved through strengthening regular antenatal care , early detection, early diagnosis and early treatment .