CAJ | 학술논문

目的：研究电针对脑卒中后抑郁(PSD)患者局部脑血流量(rCBF)的影响。方法将21例脑卒中后抑郁患者随机分为电针组(n=11)和药物组(n=10)。电针组取双侧合谷、太冲穴，每天1次；药物组口服盐酸氟西汀分散片20 mg，每天1次，均连续治疗8周。患者分别于治疗前及治疗后2、4、8周使用汉密尔顿抑郁量表(HAMD)进行评定，治疗前及治疗后8周采用单光子发射计算机断层成像(SPECT)观察rCBF的变化。结果电针组治疗后2周时HAMD低于药物组(P<0.05)，而治疗后4周、8周时无显著性差异(P>0.05)。治疗8周后，电针组rCBF较药物组改善更佳(P<0.05)。结论电针治疗脑卒中后抑郁疗效明确，可能与改善卒中后脑灌注有关。
목적：연구전침대뇌졸중후억욱(PSD)환자국부뇌혈류량(rCBF)적영향。방법장21례뇌졸중후억욱환자수궤분위전침조(n=11)화약물조(n=10)。전침조취쌍측합곡、태충혈，매천1차；약물조구복염산불서정분산편20 mg，매천1차，균련속치료8주。환자분별우치료전급치료후2、4、8주사용한밀이돈억욱량표(HAMD)진행평정，치료전급치료후8주채용단광자발사계산궤단층성상(SPECT)관찰rCBF적변화。결과전침조치료후2주시HAMD저우약물조(P<0.05)，이치료후4주、8주시무현저성차이(P>0.05)。치료8주후，전침조rCBF교약물조개선경가(P<0.05)。결론전침치료뇌졸중후억욱료효명학，가능여개선졸중후뇌관주유관。
Objective To explore the therapeutic effects of electroacupuncture on regional cerebral blood flow (rCBF) in patients with post-stroke depression. Methods 21 patients with post-stroke depression were randomly divided into electroacupuncture group (n=11) and drug group (n=10). The electroacupuncture group received electroacupuncture on double Hegu (LI4) and Taichong (LR3) once a day for 8 weeks, while the drug group took fluoxetine hydrochloride dispersible tablets 20 mg a day for 8 weeks. They were evaluated with Hamilton Self-rating Scale for Depression (HAMD) before, and 2 weeks, 4 weeks and 8 weeks after treatment respectively. The rCBF were measured with single positron emission computerized tomography (SPECT) before and 8 weeks after treatment. Results The score of HAMD de-creased more in the electroacupuncture group than in the drug group 2 weeks after treatment (P<0.05), and there was no significant differ-ence between the two groups 4 and 8 weeks after treatment (P>0.05). The rCBF was significantly greater in the electroacupuncture group than in the drug group. Conclusion That electroacupuncture is effective on post-stroke depression, which may be related with the increase of the rCBF levels.