CAJ | 학술논문

目的：探讨心脑宁胶囊在脑梗死偏瘫患者治疗和康复中的临床疗效。方法选取2012年1月至2014年1月我院神经内科收治的60例脑梗死偏瘫患者，采用随机对照方法将其分为观察组和对照组。对照组（B组）给予常规治疗、康复训练和二级预防；观察组（A 组）在此基础上口服心脑宁胶囊（贵州安泰药业有限公司，国药准字H20025697，规格：0.45 g/粒），每次1.35 g，每日3次口服，连续用药6个月。于患者入院时及系统康复训练6个月后进行神经功能残缺（NIHSS）评分，并采用Brunnstrom分级法评定肢体运动功能、Barthel氏指数（BI）评定日常生活能力（ADL）。结果经过6个月的康复治疗，60例患者NIHSS评分和BI均有不同程度改善。A组康复前后NIHSS评分差值为5.2±1.8，B组为3.5±1.3；A组康复前后BI差值为40.0±11.0，B组为21.2±7.3；A组改善程度均显著高于B组（P<0.05）。结论对于脑梗死偏瘫患者，心脑宁胶囊可有效辅助改善患者临床症状，促进神经功能恢复。
목적：탐토심뇌저효낭재뇌경사편탄환자치료화강복중적림상료효。방법선취2012년1월지2014년1월아원신경내과수치적60례뇌경사편탄환자，채용수궤대조방법장기분위관찰조화대조조。대조조（B조）급여상규치료、강복훈련화이급예방；관찰조（A 조）재차기출상구복심뇌저효낭（귀주안태약업유한공사，국약준자H20025697，규격：0.45 g/립），매차1.35 g，매일3차구복，련속용약6개월。우환자입원시급계통강복훈련6개월후진행신경공능잔결（NIHSS）평분，병채용Brunnstrom분급법평정지체운동공능、Barthel씨지수（BI）평정일상생활능력（ADL）。결과경과6개월적강복치료，60례환자NIHSS평분화BI균유불동정도개선。A조강복전후NIHSS평분차치위5.2±1.8，B조위3.5±1.3；A조강복전후BI차치위40.0±11.0，B조위21.2±7.3；A조개선정도균현저고우B조（P<0.05）。결론대우뇌경사편탄환자，심뇌저효낭가유효보조개선환자림상증상，촉진신경공능회복。
Objective To investigate the therapeutic effect of Xinnaoning capsule for hemiplegia patients with a-cute cerebral infarction. Methods A total of 60 patients with hemiplegia complicated with acute cerebral infarction from January 2012 to January 2014 were included. Patients were divided into the observation group (group A) and the control group (group B) randomly. Patients in group B were given conventional therapy and rehabilitation training, while patients in group A were given Xinnaoning capsule combined with conventional therapy and rehabilitation training. The evaluation was done before and after treatment. NIHSS was observed and Motor function was assessed with Brunnstrom Grade, ADL was assessed by Barthel Index (BI). Results After 6 month of treatment, the change of NIHSS before and after in group A (5.2±1.8) were more significant than that of group B (3.5±1.3). So did the BI [group A (40.0±11.0), group B (21.2±7.3)]. Conclusion Xinnaoning capsule can effectively improve the patients' clinical symptoms, promote neural function recov-ery.