中国现代医药杂志
中國現代醫藥雜誌
중국현대의약잡지
MODERN MEDICINE JOURNAL OF CHINA
2015年
1期
41-43
,共3页
高平%马晓英%陈玲%陆雷群
高平%馬曉英%陳玲%陸雷群
고평%마효영%진령%륙뢰군
2型糖尿病%DPP4%血糖%C肽
2型糖尿病%DPP4%血糖%C肽
2형당뇨병%DPP4%혈당%C태
Type 2%diabetes DPP4%Glucose%C-peptide
目的：研究正常人群组与2型糖尿病患者空腹及餐后2h血清DPP4活性水平。方法正常人群组29例及2型糖尿病组83例，分别记录BMI、空腹及餐后2h血糖和C肽水平，并分别测定空腹及餐后2h血清DPP4活性水平。结果正常人群组空腹DPP4活性水平为（540.58±160.22）pmol/min，餐后2h为（508.32±203.58）pmol/min；0min和120min之间无差异（P＞0.05）；2型糖尿病组空腹 DPP4活性水平为（583.12±289.28）pmol/min，餐后2h 为（638.65±316.19）pmol/min；0min和120min之间有差异（P＜0.05）；其中2型糖尿病组和正常人群组在0min的DPP4水平（P＜0.05）及120min的DPP4水平（P＜0.05）均有统计学差异。结论在正常人群中，其血清DPP4的活性水平不随进食即血糖的改变而发生变化，而在2型糖尿病患者中，无论其空腹还是餐后血清DPP4活性水平均要高于正常人群组血清DPP4的活性水平，并且随进食即血糖的改变而发生变化。
目的：研究正常人群組與2型糖尿病患者空腹及餐後2h血清DPP4活性水平。方法正常人群組29例及2型糖尿病組83例，分彆記錄BMI、空腹及餐後2h血糖和C肽水平，併分彆測定空腹及餐後2h血清DPP4活性水平。結果正常人群組空腹DPP4活性水平為（540.58±160.22）pmol/min，餐後2h為（508.32±203.58）pmol/min；0min和120min之間無差異（P＞0.05）；2型糖尿病組空腹 DPP4活性水平為（583.12±289.28）pmol/min，餐後2h 為（638.65±316.19）pmol/min；0min和120min之間有差異（P＜0.05）；其中2型糖尿病組和正常人群組在0min的DPP4水平（P＜0.05）及120min的DPP4水平（P＜0.05）均有統計學差異。結論在正常人群中，其血清DPP4的活性水平不隨進食即血糖的改變而髮生變化，而在2型糖尿病患者中，無論其空腹還是餐後血清DPP4活性水平均要高于正常人群組血清DPP4的活性水平，併且隨進食即血糖的改變而髮生變化。
목적：연구정상인군조여2형당뇨병환자공복급찬후2h혈청DPP4활성수평。방법정상인군조29례급2형당뇨병조83례，분별기록BMI、공복급찬후2h혈당화C태수평，병분별측정공복급찬후2h혈청DPP4활성수평。결과정상인군조공복DPP4활성수평위（540.58±160.22）pmol/min，찬후2h위（508.32±203.58）pmol/min；0min화120min지간무차이（P＞0.05）；2형당뇨병조공복 DPP4활성수평위（583.12±289.28）pmol/min，찬후2h 위（638.65±316.19）pmol/min；0min화120min지간유차이（P＜0.05）；기중2형당뇨병조화정상인군조재0min적DPP4수평（P＜0.05）급120min적DPP4수평（P＜0.05）균유통계학차이。결론재정상인군중，기혈청DPP4적활성수평불수진식즉혈당적개변이발생변화，이재2형당뇨병환자중，무론기공복환시찬후혈청DPP4활성수평균요고우정상인군조혈청DPP4적활성수평，병차수진식즉혈당적개변이발생변화。
Objective To research normal group and the patients with type 2 diabetes fasting and postprandial serum DPP4 activity level. Methods Recorded the BMI of 29 cases in normal group and 83 cases in type 2 diabetes group , fasting and postprandial blood glucose and c-peptide levels, and determination of fasting and postprandial serum DPP4 activity level. Results There was no difference between fasting and postprandial DPP4 activity levels in normal group (P>0.05). There was significant difference between fasting and postprandial DPP4 activity levels in type 2 diabetes group (P<0.05). Fasting and post-prandial DPP4 level were statistically significant between normal group and type 2 diabetes group. Conclusion In normal group, the level of serum DPP4 do not change with the level of glucose. But in type 2 diabetes group, their fasting and post-prandial serum DPP4 activity levels are higher than those in normal group, and change with the lever of glucose.
