CAJ | 학술논문

目的探讨新生儿及小婴儿肝脏婴儿型血管内皮瘤的诊断及治疗方法.方法回顾性分析2006年10月至2012年12月病房及门诊诊断的62例婴幼儿儿肝脏血管内皮瘤的临床资料.其中,手术治疗22例,口服激素治疗34例,不治疗随诊观察6例.结果手术组22例患儿全部存活.19例术后随诊至24个月,无复发,患儿生长发育同正常儿.激素治疗34例,随访3～6个月可见4例肿瘤缩小至2 cm以下,2例肿瘤无明显变化.随访至患儿服药后6～12个月可见34例CT显示28例肿瘤消失,6例直径明显缩小至2 cm以下,其中4例肝脏多发血管瘤均可见侵犯范围及数量减少.随诊观察6例,随访6～12个月可见4例肿瘤缩小至1 cm以下,2例肿瘤无明显变化.结论对于IHHE的治疗根据病变部位及范围可采用不同的治疗方法.
목적 탐토신생인급소영인간장영인형혈관내피류적진단급치료방법.방법 회고성분석2006년10월지2012년12월병방급문진진단적62례영유인인간장혈관내피류적림상자료.기중,수술치료22례,구복격소치료34례,불치료수진관찰6례.결과 수술조22례환인전부존활.19례술후수진지24개월,무복발,환인생장발육동정상인.격소치료34례,수방3～6개월가견4례종류축소지2 cm이하,2례종류무명현변화.수방지환인복약후6～12개월가견34례CT현시28례종류소실,6례직경명현축소지2 cm이하,기중4례간장다발혈관류균가견침범범위급수량감소.수진관찰6례,수방6～12개월가견4례종류축소지1 cm이하,2례종류무명현변화.결론 대우IHHE적치료근거병변부위급범위가채용불동적치료방법.
Objective To explore the diagnosis and treatment of infantile hepatic hemangioendothelioma (IHHE) in infants and young children.Methods The clinical data of 2006-2012 were retrospectively reviewed for 62 hospitalized cases of hepatic infantile hemangioendothelioma confirmed by postoperative pathology.And the treatments included surgery (n =22),oral corticosteroid (n =34) and passive observation (n =6).Results All of them survived postoperatively.And 19 cases had normal growth and development and there was no recurrence during a follow-up period of 24 months.In the non-surgical group,after 3-6 months of corticosteroids,computed tomography (CT) scan showed that 28 cases were cured and tumor diameter significantly shrank under 2 cm in 6 cases,including multiple liver hemangioma downsized in infiltrated areas (n =4).For observation cases,tumor diameter decreased under 1 cm (n =4) and there was no obvious change (n =2) during a follow-up period of 3-6 months.Conclusions Based upon lesion sites and extents,IHHE may be treated differently with a fair prognosis.