CAJ | 학술논문

目的：优选养心草与酸枣仁配伍安神作用的最佳配比。方法采用基线等比增减法拟定养心草与酸枣仁不同比例配伍，观察其对小鼠协同戊巴比妥钠睡眠实验的影响。结果与空白组相比，处方3，4能显著延长小鼠的睡眠时间和增加小鼠入睡率（P＜0．01），且以处方3药效最佳。结论处方3为养心草配伍酸枣仁安神作用的最佳比例。
목적：우선양심초여산조인배오안신작용적최가배비。방법채용기선등비증감법의정양심초여산조인불동비례배오，관찰기대소서협동무파비타납수면실험적영향。결과여공백조상비，처방3，4능현저연장소서적수면시간화증가소서입수솔（P＜0．01），차이처방3약효최가。결론처방3위양심초배오산조인안신작용적최가비례。
ABSTRACT:OBJECTIVE To study the optimal proportion of the compatibility of Sedum aizoon L .and Semen Ziziphus Spinosa on hypnotic effect .METHODS According to the increase-decrease baseline geometric proportion design method , different proportion compatibility of Sedum aizoon L .and Semen Ziziphus Spinosa were optimized through observing the pentobarbital-induced sleep in mice.RESULTS Compared with the control group,prescrip-tions 3,4 could extent the sleep time significantly and increased the sleep rate (P<0.01),and the prescriptions 3 was best.CONCLUSION Prescriptions 3 is the best proportion of the compatibility of Sedum aizoon L .and Semen Ziziphus Spinosa.on hypnotic effects.