CAJ | 학술논문

目的：探讨胆囊肉瘤样癌的临床病理特点、诊断及鉴别诊断。方法：分析6例胆囊肉瘤样癌的临床特点、组织病理学及免疫组织化学特点，进行随访，并复习相关文献。结果：胆囊肉瘤样癌组织病理学上以梭形细胞为主，免疫组织化学提示上皮标记及间叶标记阳性。结论：胆囊肉瘤样癌可以通过组织病理学特点、免疫组织化学标记明确诊断。目前治疗手段以根治性切除为主，但是由于该恶性肿瘤发生率较低，仍需搜集相关病例并长期随访跟踪，找到更好的治疗方法，以提高患者的生存率或生存质量。
목적：탐토담낭육류양암적림상병리특점、진단급감별진단。방법：분석6례담낭육류양암적림상특점、조직병이학급면역조직화학특점，진행수방，병복습상관문헌。결과：담낭육류양암조직병이학상이사형세포위주，면역조직화학제시상피표기급간협표기양성。결론：담낭육류양암가이통과조직병이학특점、면역조직화학표기명학진단。목전치료수단이근치성절제위주，단시유우해악성종류발생솔교저，잉수수집상관병례병장기수방근종，조도경호적치료방법，이제고환자적생존솔혹생존질량。
Objective: To investigate the clinicopathological features, diagnosis, and differential diagnosis of gallbladder sarcomatoid carcinoma. Methods: The clinical manifestations and the microscopic and immunohistochemical characteristics of six patients with gallbladder sarcomatoid carcinoma were analyzed with a follow-up period. Related literature was reviewed. Results:Immunohistochemical markers of gallbladder sarcomatoid carcinoma with spindle cell morphology were epithelial and mesenchymal positivity. Conclusion: Gallbladder sarcomatoid carcinoma could be firmly diagnosed by microscopic morphology and immunohistochemistry. Radical resection is currently used to treat such patients. However, more cases with longer follow-up period are needed to discover better treatments and improve the survival of these patients.