中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2015年
1期
14-17
,共4页
郭曦%杨丽娜%谢培英%周建兰%王丹
郭晞%楊麗娜%謝培英%週建蘭%王丹
곽희%양려나%사배영%주건란%왕단
圆锥角膜%接触镜,硬性透气性%生物力学%角膜黏滞性%角膜阻力因子
圓錐角膜%接觸鏡,硬性透氣性%生物力學%角膜黏滯性%角膜阻力因子
원추각막%접촉경,경성투기성%생물역학%각막점체성%각막조력인자
Keratoconus%Contact lens,rigid gas-permeable%Biomechanics%Corneal hysteresis%Corneal resistance factor
目的 观察圆锥角膜患者配戴1年以上RGPCL后的角膜形态、角膜厚度和角膜生物力学性能变化.方法 回顾性系列病例研究.选择诊断为中、重度圆锥角膜患者15例(30眼),平均球镜度为(-9.53±3.60)D,平均散光度为(-3.42±2.13)D.为患眼验配RGPCL,采用配对t检验比较初诊和戴镜1年后球镜度和散光度,角膜平坦K值和陡峭K值,角膜厚度值及角膜黏滞性(CH)值和角膜阻力因子(CRF)值的差异.结果 戴镜1年以上,患眼角膜陡峭K值从(49.21±4.06)D降低至(47.95±3.16)D(t=3.156,P＜0.05),角膜规则指数(SRI)及角膜不规则指数(SAI)分别从戴镜前的0.47±0.15和0.49±0.16降低至0.36±0.14和0.38±0.19(t=2.314、2.253,P＜0.05).角膜散光度由(-3.42±2.13)D减小至(-2.63±1.57)D(t=-5.270,P＜0.01).角膜厚度未见明显改变.角膜生物力学性能指标CH及CRF值分别由(8.26±0.39) mmHg和(7.53±0.56) mmHg上升至(10.23±0.49)mmHg和(9.05±0.58) mmHg(t=-5.954、-5.340,P＜0.01).结论 中、重度圆锥角膜配戴RGPCL 1年后角膜生物力学性能指标随角膜形态规则化改变而升高.角膜生物力学性能可作为圆锥角膜配戴RGPCL后疗效及病情转归的重要判定指标.
目的 觀察圓錐角膜患者配戴1年以上RGPCL後的角膜形態、角膜厚度和角膜生物力學性能變化.方法 迴顧性繫列病例研究.選擇診斷為中、重度圓錐角膜患者15例(30眼),平均毬鏡度為(-9.53±3.60)D,平均散光度為(-3.42±2.13)D.為患眼驗配RGPCL,採用配對t檢驗比較初診和戴鏡1年後毬鏡度和散光度,角膜平坦K值和陡峭K值,角膜厚度值及角膜黏滯性(CH)值和角膜阻力因子(CRF)值的差異.結果 戴鏡1年以上,患眼角膜陡峭K值從(49.21±4.06)D降低至(47.95±3.16)D(t=3.156,P＜0.05),角膜規則指數(SRI)及角膜不規則指數(SAI)分彆從戴鏡前的0.47±0.15和0.49±0.16降低至0.36±0.14和0.38±0.19(t=2.314、2.253,P＜0.05).角膜散光度由(-3.42±2.13)D減小至(-2.63±1.57)D(t=-5.270,P＜0.01).角膜厚度未見明顯改變.角膜生物力學性能指標CH及CRF值分彆由(8.26±0.39) mmHg和(7.53±0.56) mmHg上升至(10.23±0.49)mmHg和(9.05±0.58) mmHg(t=-5.954、-5.340,P＜0.01).結論 中、重度圓錐角膜配戴RGPCL 1年後角膜生物力學性能指標隨角膜形態規則化改變而升高.角膜生物力學性能可作為圓錐角膜配戴RGPCL後療效及病情轉歸的重要判定指標.
목적 관찰원추각막환자배대1년이상RGPCL후적각막형태、각막후도화각막생물역학성능변화.방법 회고성계렬병례연구.선택진단위중、중도원추각막환자15례(30안),평균구경도위(-9.53±3.60)D,평균산광도위(-3.42±2.13)D.위환안험배RGPCL,채용배대t검험비교초진화대경1년후구경도화산광도,각막평탄K치화두초K치,각막후도치급각막점체성(CH)치화각막조력인자(CRF)치적차이.결과 대경1년이상,환안각막두초K치종(49.21±4.06)D강저지(47.95±3.16)D(t=3.156,P＜0.05),각막규칙지수(SRI)급각막불규칙지수(SAI)분별종대경전적0.47±0.15화0.49±0.16강저지0.36±0.14화0.38±0.19(t=2.314、2.253,P＜0.05).각막산광도유(-3.42±2.13)D감소지(-2.63±1.57)D(t=-5.270,P＜0.01).각막후도미견명현개변.각막생물역학성능지표CH급CRF치분별유(8.26±0.39) mmHg화(7.53±0.56) mmHg상승지(10.23±0.49)mmHg화(9.05±0.58) mmHg(t=-5.954、-5.340,P＜0.01).결론 중、중도원추각막배대RGPCL 1년후각막생물역학성능지표수각막형태규칙화개변이승고.각막생물역학성능가작위원추각막배대RGPCL후료효급병정전귀적중요판정지표.
Objective To observe the changes in corneal shape,corneal thickness and corneal biomechanics in keratoconus patients who wore RGPCL for more than 1 year.Methods In this retrospective case series study,15 patients (30 eyes) with moderate or worse keratoconus were recruited.Average spherical and astigmatic powers were-9.53±3.60 D and-3.42±2.13 D,respectively.The RGPCL were fitted for diagnosed keratoconus eyes,and a paired t-test was used to compare corneal parameters between before and after 1 year of lens wear.Measured parameters included spherical and astigmatism power,corneal fiat and steep K values,corneal thickness,corneal hysteresis (CH) and the corneal resistance factor (CRF).Results Some changes occurred to keratoconus eyes after 1 year of wear:corneal steep K values decreased from 49.21±4.06 D to 47.95±3.16 D (t=3.156,P＜0.05); the corneal surface regularity index (SRI) and surface asymmetry index (SAI) decreased from 0.47±0.15 and 0.49±0.16 to 0.36±0.14 and 0.38±0.19 (t=2.314,2.253,P＜0.05); corneal astigmatism decreased from-3.42±2.13 D to-2.63±1.57 D (t=-5.270,P＜0.01); corneal thickness had no significant change; corneal biomechanical CH increased from 8.26±0.39 mmHg to 10.23±0.49 mmHg (t=-5.954,P＜0.01); and corneal biomechanical CRF increased from 7.53±0.56 mmHg to 9.05±0.58 mmHg (t=-5.340,P＜0.01).Conclusion By following the change in corneal shape after 1 year of RGPCL wear,corneal biomechanical properties have significant increases in eyes with moderate or worse keratoconus.The patient's condition and corneal biomechanics can be the key indicators for the efficacy of treating keratoconus patients with RGPCLs.
