中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2015年
1期
8-13
,共6页
王坤伟%刘军%徐炯%丁和远%盛励%查兵兵%吴跃跃%黄新梅%王芳
王坤偉%劉軍%徐炯%丁和遠%盛勵%查兵兵%吳躍躍%黃新梅%王芳
왕곤위%류군%서형%정화원%성려%사병병%오약약%황신매%왕방
白细胞计数%高血压
白細胞計數%高血壓
백세포계수%고혈압
Leulaocytes%Hypertension
目的 探讨老年高血压患者中白细胞计数与其血压控制水平的相关性. 方法 入选上海市闵行区江川社区的1919例60岁以上服用≥1种降压药物的高血压患者为研究对象.测量身高、体质量、腰围、臀围、血压,检测外周血白细胞计数、血脂、空腹血糖、血肌酐.根据血压控制水平将其分为4组:血压＜120/80 mmHg(1 mmHg=0.133 kPa)组218例、120～139/80～89 mmHg组632例、140～159/90～99mmHg组754例、≥160/100mmHg组315例. 结果 随着血压水平升高,白细胞水平逐渐升高(P＜0.05).Pearson相关分析结果显示,在男性高血压患者中,白细胞计数与收缩压、脉压、体质指数、体质量、腰围、腰臀比、三酰甘油和空腹血糖呈正相关性(r值分别为0.13、0.12、0.14、0.13、0.13、0.15、0.12和0.17,均P＜0.01).Logistic多元回归分析结果显示,在校正年龄和心血管疾病危险因素后,血压≥160/100 mmHg组白细胞计数(＞7.1×109/L)升高是＜120/80mmHg组的1.518倍(95％CI:1.003～2.298,P＜0.05);白细胞计数是收缩压及脉压的独立危险因素(均P＜0.01).以血压140/90 mmHg为分界值,白细胞与血压的受试者工作特征曲线所得白细胞的切点值为5.25×109/L. 结论 老年高血压患者血压控制水平越差,其白细胞计数越高.白细胞计数可能是血压控制水平的预测指标之一.
目的 探討老年高血壓患者中白細胞計數與其血壓控製水平的相關性. 方法 入選上海市閔行區江川社區的1919例60歲以上服用≥1種降壓藥物的高血壓患者為研究對象.測量身高、體質量、腰圍、臀圍、血壓,檢測外週血白細胞計數、血脂、空腹血糖、血肌酐.根據血壓控製水平將其分為4組:血壓＜120/80 mmHg(1 mmHg=0.133 kPa)組218例、120～139/80～89 mmHg組632例、140～159/90～99mmHg組754例、≥160/100mmHg組315例. 結果 隨著血壓水平升高,白細胞水平逐漸升高(P＜0.05).Pearson相關分析結果顯示,在男性高血壓患者中,白細胞計數與收縮壓、脈壓、體質指數、體質量、腰圍、腰臀比、三酰甘油和空腹血糖呈正相關性(r值分彆為0.13、0.12、0.14、0.13、0.13、0.15、0.12和0.17,均P＜0.01).Logistic多元迴歸分析結果顯示,在校正年齡和心血管疾病危險因素後,血壓≥160/100 mmHg組白細胞計數(＞7.1×109/L)升高是＜120/80mmHg組的1.518倍(95％CI:1.003～2.298,P＜0.05);白細胞計數是收縮壓及脈壓的獨立危險因素(均P＜0.01).以血壓140/90 mmHg為分界值,白細胞與血壓的受試者工作特徵麯線所得白細胞的切點值為5.25×109/L. 結論 老年高血壓患者血壓控製水平越差,其白細胞計數越高.白細胞計數可能是血壓控製水平的預測指標之一.
목적 탐토노년고혈압환자중백세포계수여기혈압공제수평적상관성. 방법 입선상해시민행구강천사구적1919례60세이상복용≥1충강압약물적고혈압환자위연구대상.측량신고、체질량、요위、둔위、혈압,검측외주혈백세포계수、혈지、공복혈당、혈기항.근거혈압공제수평장기분위4조:혈압＜120/80 mmHg(1 mmHg=0.133 kPa)조218례、120～139/80～89 mmHg조632례、140～159/90～99mmHg조754례、≥160/100mmHg조315례. 결과 수착혈압수평승고,백세포수평축점승고(P＜0.05).Pearson상관분석결과현시,재남성고혈압환자중,백세포계수여수축압、맥압、체질지수、체질량、요위、요둔비、삼선감유화공복혈당정정상관성(r치분별위0.13、0.12、0.14、0.13、0.13、0.15、0.12화0.17,균P＜0.01).Logistic다원회귀분석결과현시,재교정년령화심혈관질병위험인소후,혈압≥160/100 mmHg조백세포계수(＞7.1×109/L)승고시＜120/80mmHg조적1.518배(95％CI:1.003～2.298,P＜0.05);백세포계수시수축압급맥압적독립위험인소(균P＜0.01).이혈압140/90 mmHg위분계치,백세포여혈압적수시자공작특정곡선소득백세포적절점치위5.25×109/L. 결론 노년고혈압환자혈압공제수평월차,기백세포계수월고.백세포계수가능시혈압공제수평적예측지표지일.
Objective To investigate the relationship between white blood cell count (WBC) and blood pressure control in elderly patients with hypertension.Methods A cross-sectional study was conducted in 1919 patients with hypertension aged 60 years or over who took one or more antihypertensive drugs from Jiangchuan Community of Shanghai.Height,weight,waist circumference,hip circumference,blood pressure,blood white blood cell count,blood lipid,fasting blood glucose and serum creatinine were measured.Subjects were classified into four groups:BP ≥120/80 mmHg(n=218) ;120-139/80～89 mmHg(n=632) ; 140-159/90-99 mmHg(n=754) ;≥160/100 mmHg (n=315).Results White blood cell count was increased with the gradually increasing blood pressure (P＜0.05).Pearson correlation analysis showed that WBC was positively related to systolic blood pressure,pulse pressure,body mass index,weight,waist,waist hip ratio,triglyceride and fasting blood glucose levels in male subjects (r=0.13,0.12,0.14,0.13,0.13,0.15,0.12 and 0.17,all P＜0.01).Logistic regression analysis showed that the increase of WBC count was 1.518 folds higher in highest blood pressure group (≥160/100 mmHg) than in lowest blood pressure group (120/80 mmHg) (95％CI:1.003-2.298,P＜0.05) after adjusting for age and cardiovascular disease risk factors.Multiple regression analysis showed that WBC count was the independent factor for systolic blood pressure and pulse pressure (β =0.060 and 0.059,both P＜ 0.01).While BP 140/90mmHg as the boundary,the receiver operating characteristic curve (ROC) was used to evaluate the value of WBC count for blood pressure control.The optimal cut-off value of WBC was 5.25 109/L.Conclusions For the elderly patients with hypertension,the white blood cell count is increased with the poor blood pressure control.White blood cell count may be used as one of predictors for blood pressure control.
