CAJ | 학술논문

目的：探讨影响新疆维吾尔族长寿老人心血管相关危险因素。方法对新疆和田地区7个县的388名长寿老人（长寿组）及441名非长寿老人（对照组）进行流行病学调查，并测量其身高、体质量、血压、血脂等指标，比较两组差异。结果长寿组与对照组身高、体质量、BMI、DBP、脉压差、MAP、脉搏、TG、TC、HDL、LDL、HDL／LDL、Apo-B、Apo-A／Apo-B 比较，差异有统计学意义（P ＜0．05），长寿组超重、肥胖、高 TG、高 TC、低 HDL、高LDL 明显低于对照组，差异有统计学意义（P ＜0．05）。正常 BMI、高 HDL 血症、Apo-B 降低、Apo-A／Apo-B 增高为长寿老人心血管保护因素（OR ＜1），而高 LDL 血症、HDL-CH／LDL-CH 增高为长寿老人心血管危险因素（OR＞1）。结论新疆维吾尔族长寿老人心血管相关危险因素检出率与非长寿老人相比存在明显差异，可能与其遗传背景、生活环境、生活方式不同密切相关。
목적：탐토영향신강유오이족장수노인심혈관상관위험인소。방법대신강화전지구7개현적388명장수노인（장수조）급441명비장수노인（대조조）진행류행병학조사，병측량기신고、체질량、혈압、혈지등지표，비교량조차이。결과장수조여대조조신고、체질량、BMI、DBP、맥압차、MAP、맥박、TG、TC、HDL、LDL、HDL／LDL、Apo-B、Apo-A／Apo-B 비교，차이유통계학의의（P ＜0．05），장수조초중、비반、고 TG、고 TC、저 HDL、고LDL 명현저우대조조，차이유통계학의의（P ＜0．05）。정상 BMI、고 HDL 혈증、Apo-B 강저、Apo-A／Apo-B 증고위장수노인심혈관보호인소（OR ＜1），이고 LDL 혈증、HDL-CH／LDL-CH 증고위장수노인심혈관위험인소（OR＞1）。결론신강유오이족장수노인심혈관상관위험인소검출솔여비장수노인상비존재명현차이，가능여기유전배경、생활배경、생활방식불동밀절상관。
Objective To explore the distribution of risk factors associated with cardiovascular diseases in longevity elderly population in Xinjiang Uyghur.Methods By a cross-sectional research,388 individuals more than 90 years old in Xinjiang Uygur,as longevity group,and 441 persons mean age (68.1±4.7)years old in the neighbor non-elderly longevity area,as control group were studied to measure its height, weight,blood pressure,blood lipids and other indicators.Results Compared to the control group:the prevalence of height,weight,BMI,DBP,pulse pressure difference,MAP,pulses,TG,TC,HDL-CH, LDL-CH,Apo-B,Apo-A/Apo-B was significantly difference (P <0,001).The gender,HDL-CH/LDL-CH was difference (P <0.05).The overweight,obesity,high TG,high TC,low HDL-CH,high LDL-CH was significantly lower (P <0.001).normal BMI,high HDL levels,Apo-B reduced,high Apo-A/Apo-B increased promote people longevity (OR < 1),high LDL levels,HDL-CH/LDL-CH increased do not promote people longevity (OR > 1 ).Conclusion There is a significantly difference between longevity group and control group,which maybe relate to genetic background,living environment,way of life.