CAJ | 학술논문

目的：：了解我院药品不良反应( ADR)发生的特点及规律。方法：回顾性分析我院2013年收集的306例药品不良反应报告,对患者性别、年龄、给药途径、药物类别、ADR累及系统/器官和临床表现、分类情况、因果关系评价以及报告人员构成比等进行统计分析。结果：306例ADR报告中,51~60岁患者发生ADR例数构成比最高(20.26%)；给药途径以静脉滴注引起的ADR例数构成比最高(65.58%)；药品类别以抗菌药引起的ADR例数构成比最高(20.78%)；ADR累及系统以消化系统为主,占23.91%；医师报告的数量最多,占97.71%。结论：我院应加强对ADR的监测和报告,促进临床合理用药,降低ADR风险,保障患者用药安全。
목적：：료해아원약품불량반응( ADR)발생적특점급규률。방법：회고성분석아원2013년수집적306례약품불량반응보고,대환자성별、년령、급약도경、약물유별、ADR루급계통/기관화림상표현、분류정황、인과관계평개이급보고인원구성비등진행통계분석。결과：306례ADR보고중,51~60세환자발생ADR례수구성비최고(20.26%)；급약도경이정맥적주인기적ADR례수구성비최고(65.58%)；약품유별이항균약인기적ADR례수구성비최고(20.78%)；ADR루급계통이소화계통위주,점23.91%；의사보고적수량최다,점97.71%。결론：아원응가강대ADR적감측화보고,촉진림상합리용약,강저ADR풍험,보장환자용약안전。
Objective:To study the regularity and characteristics of adverse drug reaction ( ADR) in our hospital. Methods: A retrospective analysis was conducted on 306 ADR reports collected in our hospital in 2013. The reports were statistically analyzed in re-spect of sex, age, route of drug administration, drug categories, organs/systems involved in ADR and clinical manifestations, classifi-cation of ADR, causality assessment, constituent ratio of the reporters etc. Results:In the 306 ADR reports, the incidence of ADR be-tween the age of 51 and 60 was the highest (20. 26%); the ratio of the ADR induced by intravenously drip administration was the highest in respect of the route of administrations (65. 58%);the radio of ADR induced by antibacterial agents was the highest in re-spect of drug types (20. 78%);digestive system was the maln lesion in ADR cases (23. 91%). The ADR cases were mostly reported by doctors (97. 71%). Conclusion:Our hospital should enhance the ADR monitoring and reporting, promote the clinical rational drug use, reduce or avoid the risk of ADR and protect medication safety of patients.