CAJ | 학술논문

以甲醇为萃取溶剂，采用微波辅助萃取技术提取皮革及其制品中残留的限用酰胺类溶剂，提取液经固相萃取柱净化后进行气相色谱/质谱-选择离子监测法测定，外标法定量，从而建立了1个同时测定皮革及其制品中5种限用酰胺类溶剂的气质联用方法。在信噪比(S/N)=3的条件下，甲酰胺、N-甲基甲酰胺、N-甲基乙酰胺、N,N-二甲基甲酰胺、N,N-二甲基乙酰胺的检出限分别为50、10、10、25、5μg/kg。在3个不同加标水平下，平均加标回收率为86.13%~95.67%，相对标准偏差1.35%~4.28%(n=9)。该方法简单快捷，灵敏度高，检出限低，适用于皮革及其制品中限用酰胺类溶剂残留量的检测。
이갑순위췌취용제，채용미파보조췌취기술제취피혁급기제품중잔류적한용선알류용제，제취액경고상췌취주정화후진행기상색보/질보-선택리자감측법측정，외표법정량，종이건립료1개동시측정피혁급기제품중5충한용선알류용제적기질련용방법。재신조비(S/N)=3적조건하，갑선알、N-갑기갑선알、N-갑기을선알、N,N-이갑기갑선알、N,N-이갑기을선알적검출한분별위50、10、10、25、5μg/kg。재3개불동가표수평하，평균가표회수솔위86.13%~95.67%，상대표준편차1.35%~4.28%(n=9)。해방법간단쾌첩，령민도고，검출한저，괄용우피혁급기제품중한용선알류용제잔류량적검측。
An effective method was established to determine the residual contents of five banned amides in leather and leather products simultaneously. Residual amides in leather and leather products were microwave-assisted extracted, using methanol as the extraction solvent. The extract was then purified by solid-phase extraction column, followed by the analysis of gas chromatography/mass spectrometry-selected ion monitoring (GC/MS-SIM) technique. The concentration of each analyte were calibrated by external standard method. The limit of detection (LOD) was 50, 10, 10, 25 and 5 g/kg for formamide, N-methylformamide, N-methylacetamide, N,N-dimethylformamide and dimethylace-tamide, respectively, under the condition of signal to noise (S/N) of 3. The spiked average recoveries changed from 86.13% to 95.67% under three different spiked levels while the relative standard deviation (RSD) varied from 1.35%to 4.28%. The proposed method was simple, rapid, accurate and sensitive, and applicable for the determination of residual amides in leather and leather products.