CAJ | 학술논문

目的：：探讨1例卵巢成熟性畸胎瘤伴甲状腺肿类癌的临床病理特征。方法：对1例诊断为卵巢成熟性畸胎瘤伴甲状腺肿类癌患者的临床资料、组织学形态及免疫组化结果进行分析，并对相关文献进行复习。结果：本例为卵巢成熟性畸胎瘤伴甲状腺肿类癌，病理学检查除成熟性畸胎瘤成分外，另见由甲状腺和类癌组织混合成的结节一枚，类癌细胞较小且大小相仿，染色质均匀，核分裂少见，免疫组化：甲状腺滤泡上皮细胞TG(+)、TTF-1(+)，类癌细胞CD99(+)、CgA(+)、Syn(+)、CK7(-)。结论：卵巢成熟性畸胎瘤伴甲状腺肿类癌为罕见的病变，临床患者多无典型症状，且类癌成分多与甲状腺组织混杂于畸胎瘤中，容易漏诊，故应广泛取材并提高对卵巢成熟性畸胎瘤伴甲状腺肿类癌组织学特征及免疫表型的认识，对累积资料，避免临床误诊、漏诊具有重要的价值。
목적：：탐토1례란소성숙성기태류반갑상선종유암적림상병리특정。방법：대1례진단위란소성숙성기태류반갑상선종유암환자적림상자료、조직학형태급면역조화결과진행분석，병대상관문헌진행복습。결과：본례위란소성숙성기태류반갑상선종유암，병이학검사제성숙성기태류성분외，령견유갑상선화유암조직혼합성적결절일매，유암세포교소차대소상방，염색질균균，핵분렬소견，면역조화：갑상선려포상피세포TG(+)、TTF-1(+)，유암세포CD99(+)、CgA(+)、Syn(+)、CK7(-)。결론：란소성숙성기태류반갑상선종유암위한견적병변，림상환자다무전형증상，차유암성분다여갑상선조직혼잡우기태류중，용역루진，고응엄범취재병제고대란소성숙성기태류반갑상선종유암조직학특정급면역표형적인식，대루적자료，피면림상오진、루진구유중요적개치。
Objective: To discuss the clinicopathologic features of ovarian mature cystic teratoma with strumal carcinoid. Methods: Clinical data,pathological diagnosis and immunohistochemical results of a case of ovarian mature cystic teratoma with strumal carcinoid were analyzed,and related literatures were reviewed. Results: This case was an ovarian mature cystic teratoma, histopathological examination revealed a nodule of strumal carcinoid. It mainly consisted of unequal-sized thyriod follicle and carcinoid cells. Thyriod follicle epithelial cells were positive for TG and TTF-1 and carcinoid cells were positive for CD99, CgA, Syn, but nagtive for CK7. Conclusions: Ovarian mature cystic teratoma with strumal carcinoid is a rare disease. It usually lack of typical clinical symptom and carcinoid cells always mix with thyriod tissue. It is easilly misdiagnosed. Therefore careful gross examination, extensive sampling and immunohistochemical exam are very important for its correct diagnosis.