中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
5期
859-860,861
,共3页
复方独胜软膏%质量标准%桂皮醛%阿魏酸%高效液相色谱法
複方獨勝軟膏%質量標準%桂皮醛%阿魏痠%高效液相色譜法
복방독성연고%질량표준%계피철%아위산%고효액상색보법
Fufang Dusheng ointments%Quality standard%Cinnamaldehyde%Ferulic acid%HPLC
目的：：建立复方独胜软膏质量标准。方法：采用TLC法对复方独胜软膏中当归、桂枝进行定性鉴别；用HPLC法对制剂中桂皮醛进行含量测定。结果：定性鉴别分离度较好,专属性强；桂皮醛的含量测定线性范围为5.025~50.255μg· ml-1(r=0.9999),平均回收率为98.92%,RSD=1.64%(n=9)。结论：所建立方法准确可靠,灵敏度高,专属性强,能有效控制复方独胜软膏的质量。
目的：：建立複方獨勝軟膏質量標準。方法：採用TLC法對複方獨勝軟膏中噹歸、桂枝進行定性鑒彆；用HPLC法對製劑中桂皮醛進行含量測定。結果：定性鑒彆分離度較好,專屬性彊；桂皮醛的含量測定線性範圍為5.025~50.255μg· ml-1(r=0.9999),平均迴收率為98.92%,RSD=1.64%(n=9)。結論：所建立方法準確可靠,靈敏度高,專屬性彊,能有效控製複方獨勝軟膏的質量。
목적：：건립복방독성연고질량표준。방법：채용TLC법대복방독성연고중당귀、계지진행정성감별；용HPLC법대제제중계피철진행함량측정。결과：정성감별분리도교호,전속성강；계피철적함량측정선성범위위5.025~50.255μg· ml-1(r=0.9999),평균회수솔위98.92%,RSD=1.64%(n=9)。결론：소건립방법준학가고,령민도고,전속성강,능유효공제복방독성연고적질량。
Objective: To establish the quality standard for Fufang Dusheng ointments. Methods: Angelicae sinensis radix and Cinnamomi ramulus in Fufang Dusheng ointments were identified by TLC. Cinnamaldehyde was determined by HPLC. Results: The characteristic identification by TLC was distinct and highly specific. Cinnamaldehyde had the linear range of 5. 025-50. 255 μg·ml-1 (r=0. 999 9), and the average recovery was 98. 92% (RSD=1. 64%, n=9). Conclusion: The method is reliable, accurate and specific. It can be used in the quality control of Fufang Dusheng ointments.
