中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
5期
876-877
,共2页
抗氧剂1178%高效液相色谱%五层共挤输液用袋
抗氧劑1178%高效液相色譜%五層共擠輸液用袋
항양제1178%고효액상색보%오층공제수액용대
Antioxygen 1178%HPLC%5-Layer co-extrusion bags used for infusion
目的：：建立五层共挤输液用袋中抗氧剂1178的含量测定方法。方法：色谱柱：Uitimat XB-C8(250 mm ×4.6 mm,5μm),流动相：甲醇-水梯度洗脱,流速：1.0 ml·min-1,检测波长：223 nm,柱温：35℃,进样量20μl。结果：抗氧剂1178在1.64~205.10μg·ml-1范围内线性关系良好(r=0.9999),平均回收率为92.05%,RSD=1.94%(n=9)。结论：建立的方法结果准确、稳定性好、专属性强,可用于五层共挤输液用袋中抗氧剂1178的含量测定。
目的：：建立五層共擠輸液用袋中抗氧劑1178的含量測定方法。方法：色譜柱：Uitimat XB-C8(250 mm ×4.6 mm,5μm),流動相：甲醇-水梯度洗脫,流速：1.0 ml·min-1,檢測波長：223 nm,柱溫：35℃,進樣量20μl。結果：抗氧劑1178在1.64~205.10μg·ml-1範圍內線性關繫良好(r=0.9999),平均迴收率為92.05%,RSD=1.94%(n=9)。結論：建立的方法結果準確、穩定性好、專屬性彊,可用于五層共擠輸液用袋中抗氧劑1178的含量測定。
목적：：건립오층공제수액용대중항양제1178적함량측정방법。방법：색보주：Uitimat XB-C8(250 mm ×4.6 mm,5μm),류동상：갑순-수제도세탈,류속：1.0 ml·min-1,검측파장：223 nm,주온：35℃,진양량20μl。결과：항양제1178재1.64~205.10μg·ml-1범위내선성관계량호(r=0.9999),평균회수솔위92.05%,RSD=1.94%(n=9)。결론：건립적방법결과준학、은정성호、전속성강,가용우오층공제수액용대중항양제1178적함량측정。
Objective:To establish a method for the determination of antioxygen 1178 in 5-layer co-extrusion bags used for infu-sion. Methods:A Uitimat XB-C8 (250 mm × 4. 6 mm,5μm) column was used,the mobile phase was methanol-water with gradient elu-tion, the flow rate was 1. 0 ml·min-1 ,the detection wavelength was 223 nm,the column temperature was 35℃ and the injection vol-ume was 20 μl. Results:The concentration of antioxygen 1178 had the linear relationship within the range of 1. 64-205. 10 μg·ml-1 (r=0. 999 9),and the average recovery was 92. 05% (RSD=1. 94%, n=9). Conclusion:The method is accurate,stable and spe-cific,and can be used to determine antioxygen 1178 in 5-layer co-extrusion bags used for infusion.
