CAJ | 학술논문

目的：观察老年2型糖尿病患者采用甘精胰岛素治疗的临床效果。方法120例患有2型糖尿病的老年患者，将其随机分为对照组和观察组，每组60例，对照组采用精蛋白锌重组赖脯胰岛素治疗，观察组采用甘精胰岛素治疗。对比两组疗效。结果观察组患者治疗后的低血糖的发生率(13.33%)明显低于对照组(41.67%)，观察组患者治疗后餐后2 h的血糖和空腹血糖、血糖达标时间、糖化血红蛋白(HbA1c)水平均好于对照组患者，两组比较差异具有统计学意义(P<0.05)。结论甘精胰岛素治疗老年患者2型糖尿病可缩短患者的血糖达标时间，治疗方案经济、安全、有效，临床价值较高。
목적：관찰노년2형당뇨병환자채용감정이도소치료적림상효과。방법120례환유2형당뇨병적노년환자，장기수궤분위대조조화관찰조，매조60례，대조조채용정단백자중조뢰포이도소치료，관찰조채용감정이도소치료。대비량조료효。결과관찰조환자치료후적저혈당적발생솔(13.33%)명현저우대조조(41.67%)，관찰조환자치료후찬후2 h적혈당화공복혈당、혈당체표시간、당화혈홍단백(HbA1c)수평균호우대조조환자，량조비교차이구유통계학의의(P<0.05)。결론감정이도소치료노년환자2형당뇨병가축단환자적혈당체표시간，치료방안경제、안전、유효，림상개치교고。
Objective To observe the clinical effect of insulin glargine in the treatment of senile type 2 diabetes mellitus patients. Methods A total of 120 senile patients with type 2 diabetes mellitus were randomly divided into control group and observation group, with 60 cases in each group. The control group received insulin protamine zinc restructuring lispro for treatment, and the observation group received insulin glargine for treatment. Curative effects of the two groups were compared. Results The observation group had much lower incidence of hypoglycemia (13.33%) than the control group (41.67%) after treatment. The observation group also had better levels of 2 h postprandial blood glucose, fasting blood-glucose, blood glucose standard time, and glycosylated hemoglobin (HbA1c) than the control group. The differences between the two groups had statistical significance (P<0.05). Conclusion Insulin glargine can shorten blood glucose standard time in treating senile type 2 diabetes mellitus patients, and this method contains high clinical value as economical, safe and effective.