医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2015年
8期
173-174
,共2页
类风湿性关节炎(RA)%环瓜氨酸肽(CCP)%类风湿因子(RF)%C反应蛋白(CRP)
類風濕性關節炎(RA)%環瓜氨痠肽(CCP)%類風濕因子(RF)%C反應蛋白(CRP)
류풍습성관절염(RA)%배과안산태(CCP)%류풍습인자(RF)%C반응단백(CRP)
Rheumatoid arthritis%Ring citrulline peptide%Rheumatoid factor%C-reactive protein
目的：探讨血清抗CCP、RF 和CRP 的联合检测对类风湿性关节炎的诊断价值。方法：检测抗CCP采用ELISA法，检测RF、CRP采用免疫比浊法，共检测52例类风湿关节炎患者和55例健康体检者，并进行比较分析。结果：类风湿关节炎患者组血清抗CCP、RF 和CRP结果显著高于对照组，P＜0.01，差异有统计学意义。联合检测的敏感性、特异性、准确度分别为82.7%(43/52)、94.5%(52/55)、93.1（95/102），均高于单项检测结果。结论：血清抗CCP、RF 和CRP的联合检测有助于提高类风湿性关节炎的诊断率。
目的：探討血清抗CCP、RF 和CRP 的聯閤檢測對類風濕性關節炎的診斷價值。方法：檢測抗CCP採用ELISA法，檢測RF、CRP採用免疫比濁法，共檢測52例類風濕關節炎患者和55例健康體檢者，併進行比較分析。結果：類風濕關節炎患者組血清抗CCP、RF 和CRP結果顯著高于對照組，P＜0.01，差異有統計學意義。聯閤檢測的敏感性、特異性、準確度分彆為82.7%(43/52)、94.5%(52/55)、93.1（95/102），均高于單項檢測結果。結論：血清抗CCP、RF 和CRP的聯閤檢測有助于提高類風濕性關節炎的診斷率。
목적：탐토혈청항CCP、RF 화CRP 적연합검측대류풍습성관절염적진단개치。방법：검측항CCP채용ELISA법，검측RF、CRP채용면역비탁법，공검측52례류풍습관절염환자화55례건강체검자，병진행비교분석。결과：류풍습관절염환자조혈청항CCP、RF 화CRP결과현저고우대조조，P＜0.01，차이유통계학의의。연합검측적민감성、특이성、준학도분별위82.7%(43/52)、94.5%(52/55)、93.1（95/102），균고우단항검측결과。결론：혈청항CCP、RF 화CRP적연합검측유조우제고류풍습성관절염적진단솔。
Objective To explore the serum anti CCP, the combination of RF and CRP detection value to the diagnosis of rheumatoid arthritis. Methods Detecting anti CCP using ELISA method, RF, CRP by immune turbidimetry, a total of 52 cases of patients with rheumatoid arthritis (ra) and 55 cases of healthy check-up, and comparative analysis. Results A group of patients with rheumatoid arthritis (ra) serum anti CCP, RF, and the result of the CRP is significantly higher than the control group, P<0.01, the difference was statistically significant. Joint detection sensitivity, specificity and accuracy were 82.7%(43/52), 94.5%(52/55) and 93.1 (95/102), are higher than individual test results. Conclusions Serum anti CCP, RF and joint detection of CRP is helpful to improve the diagnosis of rheumatoid arthritis.
