中国现代药物应用
中國現代藥物應用
중국현대약물응용
CHINESE JOURNAL OF MODERN DRUG APPLICATION
2015年
11期
7-8,9
,共3页
岑惠玲%郑文雅%潘淑玲
岑惠玲%鄭文雅%潘淑玲
잠혜령%정문아%반숙령
微生态制剂%蓝光照射%新生儿%黄疸%临床疗效
微生態製劑%藍光照射%新生兒%黃疸%臨床療效
미생태제제%람광조사%신생인%황달%림상료효
Microecologics%Blue light irradiation%Newborn%Jaundice%Clinical effect
目的：观察微生态制剂联合蓝光照射治疗新生儿黄疸的疗效。方法100例黄疸新生儿，随机分为三组。实验组34例，给予微生态制剂枯草杆菌二联活菌颗粒(妈咪爱)联合蓝光照射治疗；对照组33例，给予蓝光照射治疗；空白组33例，给予妈咪爱治疗。观察三组的治疗效果。结果治疗有效率以实验组最高(94.12%)；黄疸减退时间以实验组最快[平均(37.72±3.78)h]；治疗后72 h经皮胆红素较治疗前下降，以实验组最低[平均(139.78±38.33)μmol/L]；与其他两组比较，差异均具有统计学意义(P<0.05)。不良反应发生率均较低，但实验组最低，三组比较，差异无统计学意义(P>0.05)。结论微生态制剂联合蓝光照射治疗新生儿黄疸临床效果确切，黄疸减退快速，不良反应少，适合在临床推广。
目的：觀察微生態製劑聯閤藍光照射治療新生兒黃疸的療效。方法100例黃疸新生兒，隨機分為三組。實驗組34例，給予微生態製劑枯草桿菌二聯活菌顆粒(媽咪愛)聯閤藍光照射治療；對照組33例，給予藍光照射治療；空白組33例，給予媽咪愛治療。觀察三組的治療效果。結果治療有效率以實驗組最高(94.12%)；黃疸減退時間以實驗組最快[平均(37.72±3.78)h]；治療後72 h經皮膽紅素較治療前下降，以實驗組最低[平均(139.78±38.33)μmol/L]；與其他兩組比較，差異均具有統計學意義(P<0.05)。不良反應髮生率均較低，但實驗組最低，三組比較，差異無統計學意義(P>0.05)。結論微生態製劑聯閤藍光照射治療新生兒黃疸臨床效果確切，黃疸減退快速，不良反應少，適閤在臨床推廣。
목적：관찰미생태제제연합람광조사치료신생인황달적료효。방법100례황달신생인，수궤분위삼조。실험조34례，급여미생태제제고초간균이련활균과립(마미애)연합람광조사치료；대조조33례，급여람광조사치료；공백조33례，급여마미애치료。관찰삼조적치료효과。결과치료유효솔이실험조최고(94.12%)；황달감퇴시간이실험조최쾌[평균(37.72±3.78)h]；치료후72 h경피담홍소교치료전하강，이실험조최저[평균(139.78±38.33)μmol/L]；여기타량조비교，차이균구유통계학의의(P<0.05)。불량반응발생솔균교저，단실험조최저，삼조비교，차이무통계학의의(P>0.05)。결론미생태제제연합람광조사치료신생인황달림상효과학절，황달감퇴쾌속，불량반응소，괄합재림상추엄。
Objective To observe the curative effect of microecologics combined with blue light irradiation in the treatment of neonatal jaundice. Methods A total of 100 newborns with jaundice were randomly divided into three groups. Experimental group with 34 cases received microecologics bacillus subtilis duplex viable bacterium granule (Medilac-Vita) combined with blue light irradiation. Control group with 33 cases received blue light irradiation for treatment. Blank group with 33 cases received Medilac-Vita for treatment. Curative effects of the three groups were observed. Results The experimental group had the highest effective rate (94.12%) and the fastest disappearance time of jaundice [average time as (37.72±3.78) h]. In 72 h after treatment, the experimental group had the lowest level of transcutaneous bilirubin [average level as (139.78±38.33)μmol/L]. The differences from the other two groups all had statistical significance (P<0.05). All three groups had decreased incidence of adverse reactions, while the experimental group had the lowest one. Their difference had no statistical significance (P>0.05). Conclusion Combination of microecologics and blue light irradiation can provide precise effect in treating neonatal jaundice, with quick disappearance of jaundice and few adverse reactions. This method is suitable for clinical promotion.
