CAJ | 학술논문

目的：：观察复方白及乳膏治疗Ⅱ度手部皲裂的疗效及安全性。方法：146例Ⅱ度手部皲裂患者随机分为观察组和对照组各73例。观察组予复方白及乳膏治疗,对照组予尿素软膏治疗,10 d为1疗程。比较两组痛疼消失时间、角质软化时间、皲裂愈合时间,观察并评价两组疗效和药品不良反应。结果：用药1个疗程后,观察组治愈率94.5%,高于对照组的82.2%(P<0.05)；两组总有效率均为100.0%,差异无统计学意义(P>0.05)。观察组患者角质软化时间、皲裂愈合时间均显著低于对照组患者(P<0.05)；而两组痛疼消失时间比较,差异无统计学意义(P>0.05)。结论：复方白及乳膏治疗Ⅱ度手部皲裂疗效显著,安全性好,具有良好的临床应用价值。
목적：：관찰복방백급유고치료Ⅱ도수부군렬적료효급안전성。방법：146례Ⅱ도수부군렬환자수궤분위관찰조화대조조각73례。관찰조여복방백급유고치료,대조조여뇨소연고치료,10 d위1료정。비교량조통동소실시간、각질연화시간、군렬유합시간,관찰병평개량조료효화약품불량반응。결과：용약1개료정후,관찰조치유솔94.5%,고우대조조적82.2%(P<0.05)；량조총유효솔균위100.0%,차이무통계학의의(P>0.05)。관찰조환자각질연화시간、군렬유합시간균현저저우대조조환자(P<0.05)；이량조통동소실시간비교,차이무통계학의의(P>0.05)。결론：복방백급유고치료Ⅱ도수부군렬료효현저,안전성호,구유량호적림상응용개치。
Objective:To observe the clinical efficacy and safety of compound Bletilla Striata cream in the treatment of patients with second degree hand rhagadia. Methods: Totally 146 patients with second degree hand rhagadia were randomly divided into the treatment group and the control group with 73 cases in each. The treatment group was treated with compound Bletilla Striata cream, while the control group was treated with urea ointment. The treatment course was 10 days. The time of paln disappearance, keratoder-ma softening and rhagadia healing were compared between the two groups, and the efficacy and adverse drug reactions of the two groups were also observed and compared. Results:After the first treatment course, the curative rate of the treatment group was 94. 5%, which was higher than that of the control group (82. 2%) with statistical significance (P<0. 05). The total effective rate of the two groups was both 100% without statistical significance (P>0. 05). The time of keratoderma softening and rhagadia healing in the treatment group was significant shorter than that in the control group (P<0. 05), while the time of paln disappearance showed no significant difference between the two groups(P>0. 05). Conclusion: Compound Bletilla Striata cream in the treatment of second degree hand rhagadia is effective and safe, which shows good prospect for clinical application.