CAJ | 학술논문

多种传播体的交互作用会改变彼此的传播阈值和传播范围，这为病毒的免疫方法提供了新的思路。免疫体可以像病毒一样在宿主群中传播。被免疫体感染的宿主将免于被病毒感染，同时还可以将免疫体传播到它的邻居。针对病毒和免疫体在同一群体但在不同传播途径上传播的情形，采用仓室理论在双层耦合网络上建立了两种传播体交互传播的模型，并提出了评价免疫效果的指标。在人工合成网络和实际网络上的模拟表明，免疫传播可以显著降低病毒的传播范围和速度，并且存在低资源消耗和高免疫效果的理想免疫参数点。免疫传播对病毒传播有显著的抑制作用。
다충전파체적교호작용회개변피차적전파역치화전파범위，저위병독적면역방법제공료신적사로。면역체가이상병독일양재숙주군중전파。피면역체감염적숙주장면우피병독감염，동시환가이장면역체전파도타적린거。침대병독화면역체재동일군체단재불동전파도경상전파적정형，채용창실이론재쌍층우합망락상건립료량충전파체교호전파적모형，병제출료평개면역효과적지표。재인공합성망락화실제망락상적모의표명，면역전파가이현저강저병독적전파범위화속도，병차존재저자원소모화고면역효과적이상면역삼수점。면역전파대병독전파유현저적억제작용。
The interaction propagations between multiple pathogens can change propagation threshold and steady-state density of each other.This provides a new thinking of the virus immune method.This paper developed an interaction spread model be-tween viruses and immune agents using compartment theory on the double coupling networks and proposed the evaluation inde-xes of immune effect.The immune agents could spread in host group just as the viruses do.Each node infected by immune agents would be free from viruses and propagate immune agents to its neighbor nodes with some probability.Viruses and im-mune agents may spread in the same host group but different transmission pathway.Simulation experiments show that immune transmissions reduce significantly the range and speed of virus transmissions on the synthetic networks and real networks.There are ideal immune parameters with low resource consumption and highly immune effect.The spread method of immunization a-gents can bring obviously immune effects on the virus prevention.