CAJ | 학술논문

目的：了解中剂量UVA1光疗对斑块状硬皮病的临床疗效。方法：对11例斑块状硬皮病患者采用中剂量UVA1（30 J／cm2）局部治疗30次，以皮损弹性、面积、颜色、疼痛、硬度变化等指标设计临床疗效评价表，对皮损治疗前、中、后行组织病理检查，结束后随访6月，观察疗效。结果：治疗后患者临床疗效评分明显下降（Z＝－3.85，P＜0.05），组织病理表现改善，临床疗效随访6月无变化。结论：中剂量UVA1治疗斑块状硬皮病疗效肯定。
목적：료해중제량UVA1광료대반괴상경피병적림상료효。방법：대11례반괴상경피병환자채용중제량UVA1（30 J／cm2）국부치료30차，이피손탄성、면적、안색、동통、경도변화등지표설계림상료효평개표，대피손치료전、중、후행조직병리검사，결속후수방6월，관찰료효。결과：치료후환자림상료효평분명현하강（Z＝－3.85，P＜0.05），조직병리표현개선，림상료효수방6월무변화。결론：중제량UVA1치료반괴상경피병료효긍정。
Objective:To investigate the clinical efficacy of medium-dose ultraviolet A1 photo-therapy in the treatment of plaque-like morphea.Methods:11 patients with plaque-like morphea were treated with medium-dose(30 J/cm2 ) ultraviolet A1 phototherapy.Each patient was treated for 30 sessions.Clinical evaluation was assessed by a scoring system created by elasticity, area, colour, pain and hardening of lesional plaques improved.Skin lesions were received 3 times path-ologic biopsies during treatment.The patients were followed up for 6 months.The efficacy after treatment were observed.Results:After 30-sessions of treatment, the scores of lesions were signifi-cantly reduced (Z=-3.85,P<0.05),clinical pathological manifestations improved.The clini-cal effect have no change after 6 months follow up.Conclusion:Medium-dose ultraviolet A1 pho-totherapy is effective for plaque-like morphea.