CAJ | 학술논문

目的：分析评价β2-微球蛋白、尿微量白蛋白在肾损害患者中的临床效能。方法选择山东省金乡县人民医院2014年01月至2014年08月慢性肾病患者74例及选择同期在本院体检的健康体检者66例。分别为肾病组和正常对照组，同时检测两组β2-微球蛋白、血肌酐、尿微量白蛋白水平。结果与正常对照组相比，肾病组β2-微球蛋白（β2- MG）、血肌酐（SCr）监测水平明显高于对照组，差异有统计学意义（P ＜0.05）；病例组曲线下面积由高到底依次为β2-微球蛋白、血肌酐、尿微量白蛋白（UmALB）。结论相比其他指标β2-微球蛋白对肾损害患者临床诊断具有较高诊断价值。
목적：분석평개β2-미구단백、뇨미량백단백재신손해환자중적림상효능。방법선택산동성금향현인민의원2014년01월지2014년08월만성신병환자74례급선택동기재본원체검적건강체검자66례。분별위신병조화정상대조조，동시검측량조β2-미구단백、혈기항、뇨미량백단백수평。결과여정상대조조상비，신병조β2-미구단백（β2- MG）、혈기항（SCr）감측수평명현고우대조조，차이유통계학의의（P ＜0.05）；병례조곡선하면적유고도저의차위β2-미구단백、혈기항、뇨미량백단백（UmALB）。결론상비기타지표β2-미구단백대신손해환자림상진단구유교고진단개치。
Objective:To analysis and evaluation β2 - microglobulin,microalbuminuria in patients with renal impair-ment in clinical efficacy. Methods:The research object were come from Jinxiang County,Shandong Province,Peopleˊs Hospital from January 2014 to August 2014 ,74 cases of patients with chronic kidney disease and 66 cases of healthy a-dults. Respectively nephropathy group and normal control group,Detection the two group’s levels of β2 - microglobulin, urinary albumin,serum creatinine . Results:Compared with normal control group nephropathy β2 - microglobulin,serum creatinine levels were significantly higher in the monitoring,the difference was statistically significant(P < 0. 05);The pa-tient group’s area under the curve from high to the end were β2 - microglobulin,serum creatinine and urine albumin. Conclusion:Compared with the other indicators,β2 - microglobulin has a high diagnostic value in patients with clinical di-agnosis of renal damage.