CAJ | 학술논문

目的：探讨10 g/L盐酸环喷托酯滴眼液在小儿屈光状态检查中的应用。比较其与阿托品在散瞳验光中麻痹睫状肌的效果,用以指导临床工作。 　　方法：采用自身配对设计方法,对年龄3~12岁118例236眼(其中近视40例80眼,远视78例156眼,合并有散光73例146眼)先采用10 g/L盐酸环喷托酯滴眼液滴眼3次散瞳(每次间隔5min),末次点眼1h后进行检影验光。间隔3d后重新点10g/L阿托品眼膏1wk(每晚1次)重新进行散瞳检影验光。按屈光度分成近视组、远视组、散光组,其中散光度数是将柱镜度数独立分离出来统计。将两种散瞳药的验光结果进行比较。 　　结果：近视组使用两种方法散瞳验光后屈光度值分别为-2.25±1.31D,-2.23±1.32D,差异无统计学意义( P=0.109)；远视组应用两种药物散瞳验光后屈光度分别为3.76±2.4D,4.39±2.6D,差异有统计学意义(P=0.000)；散光组应用两种药物散瞳验光后屈光度值分别为1.35±1.19D,1.38±2.00D,差异无统计学意义(P=0.374)。 　　结论：盐酸环喷托酯滴眼液可用于临床上3~12岁近视、散光儿童的散瞳验光。但在远视儿童初次就诊仍需点阿托品眼膏散瞳验光。
목적：탐토10 g/L염산배분탁지적안액재소인굴광상태검사중적응용。비교기여아탁품재산동험광중마비첩상기적효과,용이지도림상공작。 　　방법：채용자신배대설계방법,대년령3~12세118례236안(기중근시40례80안,원시78례156안,합병유산광73례146안)선채용10 g/L염산배분탁지적안액적안3차산동(매차간격5min),말차점안1h후진행검영험광。간격3d후중신점10g/L아탁품안고1wk(매만1차)중신진행산동검영험광。안굴광도분성근시조、원시조、산광조,기중산광도수시장주경도수독립분리출래통계。장량충산동약적험광결과진행비교。 　　결과：근시조사용량충방법산동험광후굴광도치분별위-2.25±1.31D,-2.23±1.32D,차이무통계학의의( P=0.109)；원시조응용량충약물산동험광후굴광도분별위3.76±2.4D,4.39±2.6D,차이유통계학의의(P=0.000)；산광조응용량충약물산동험광후굴광도치분별위1.35±1.19D,1.38±2.00D,차이무통계학의의(P=0.374)。 　　결론：염산배분탁지적안액가용우림상상3~12세근시、산광인동적산동험광。단재원시인동초차취진잉수점아탁품안고산동험광。
AIM:To explore the application of 10g/L cyclopentolate chloride eye drops in children, and to compare the different effectiveness of cycloplegia between 10g/L cyclopentolate chloride and atropine in Chinese children.METHODS:A total of 236 eyes of 118 children aged 3~12 years old were enrolled in this study including 80 eyes of 40 children with myopia, 156 eyes of 78 children with hyperopia and 146 eyes of 73 children combined with astigmatism. 10g/L cyclopentolate chloride eye drops were used once per 5min for 3 times and refractive diopter was obtained 1h after the last drop of cyclopentolate. Three days after that, 10g/L atropine was then used 1 time per night for 1wk and optometry was performed again. The children were divided into 3 groups ( myopia, hyperopia and astigmatism group ) according to the refractive status, in which astigmatism was independent of the degree of separation of cylinder statistics. The results of retinoscope refraction were then compared between 10g/L cyclopentolate and 10g/L atropine. RESULTS:The refractive diopter was -2. 25±1. 31D after 10g/L cyclopentolate eye drops and -2. 23±1. 32D after 10g/L atropine in myopic group. The refractive diopter was 1. 35±1. 19D and 1. 38±2. 00D in astigmastic group. No significant difference was found in myopic group and astigmastic group (P= 0. 109, P= 0. 374). While in the hyperopic group, the refractive diopter was 3. 76±2. 4D after 10g/L cyclopentolate eye drops, which was lower than that after 10g/L atropine 4. 39±2. 6D (P=0. 000). CONCLUSION: The results of this study suggest that 10g/L cyclopentolate chloride eye drops can be used in myopia and astigmatism children, and 10g/L atropine should be used in hyperopia children.