国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2015年
4期
646-649
,共4页
软性接触镜%共焦显微镜%角膜
軟性接觸鏡%共焦顯微鏡%角膜
연성접촉경%공초현미경%각막
soft contact lens%confocal microscopy%cornea
目的：探讨配戴不同时间软性接触镜( SCL)后对患者角膜组织的病理变化。<br> 方法：应用共焦显微镜分别检查中低度近视SCL组(150例)和对照组(150例)戴镜1,3,5,8,10a以上的中央角膜和周边角膜的变化。<br> 结果：戴镜5 a后SCL组中央角膜基底细胞密度低于对照组(P<0.05),上皮层可见微小囊泡及类似角膜营养不良的角膜小滴,上皮下Langerhans细胞密度及神经纤维曲折度大于对照组( P<0.05)。 SCL组中央角膜浅基质层细胞密度低于对照组(P<0.05),各组基质层中白色点状物密度均高于对照组( P<0.05)。 SCL组内皮细胞形态变化明显,但两组内皮细胞密度无差异( P>0.05)。 SCL组中央角膜上皮层厚度小于对照组(P<0.05)。<br> 结论：SCL引起角膜组织的改变随戴镜时间的延长逐渐明显,且这种改变不容忽视。
目的：探討配戴不同時間軟性接觸鏡( SCL)後對患者角膜組織的病理變化。<br> 方法：應用共焦顯微鏡分彆檢查中低度近視SCL組(150例)和對照組(150例)戴鏡1,3,5,8,10a以上的中央角膜和週邊角膜的變化。<br> 結果：戴鏡5 a後SCL組中央角膜基底細胞密度低于對照組(P<0.05),上皮層可見微小囊泡及類似角膜營養不良的角膜小滴,上皮下Langerhans細胞密度及神經纖維麯摺度大于對照組( P<0.05)。 SCL組中央角膜淺基質層細胞密度低于對照組(P<0.05),各組基質層中白色點狀物密度均高于對照組( P<0.05)。 SCL組內皮細胞形態變化明顯,但兩組內皮細胞密度無差異( P>0.05)。 SCL組中央角膜上皮層厚度小于對照組(P<0.05)。<br> 結論：SCL引起角膜組織的改變隨戴鏡時間的延長逐漸明顯,且這種改變不容忽視。
목적：탐토배대불동시간연성접촉경( SCL)후대환자각막조직적병리변화。<br> 방법：응용공초현미경분별검사중저도근시SCL조(150례)화대조조(150례)대경1,3,5,8,10a이상적중앙각막화주변각막적변화。<br> 결과：대경5 a후SCL조중앙각막기저세포밀도저우대조조(P<0.05),상피층가견미소낭포급유사각막영양불량적각막소적,상피하Langerhans세포밀도급신경섬유곡절도대우대조조( P<0.05)。 SCL조중앙각막천기질층세포밀도저우대조조(P<0.05),각조기질층중백색점상물밀도균고우대조조( P<0.05)。 SCL조내피세포형태변화명현,단량조내피세포밀도무차이( P>0.05)。 SCL조중앙각막상피층후도소우대조조(P<0.05)。<br> 결론：SCL인기각막조직적개변수대경시간적연장축점명현,차저충개변불용홀시。
AIM:To investigate the corneal histopathology changes induced by soft contact lenses ( SCL) at diffent time. <br> METHODS: Central and peripheral cornea structures of myopic patients wearing SCL (150 cases) and the control goups ( 150 cases ) were observed with confocal microscopy. The examinations were performed 1, 3, 5, 8 and 10a after contact lenses wearing respectively. <br> RESULTS: After wearing the contact lenses for 5a, the cell density of corneal surface epithelial was lower in SCL wearers compared with control goups (P<0. 05) and the corneal vesicle and corneal gutata might be occasionally discovered. The density of Langerhans cells both in the central and peripheral cornea was higher in SCL group ( P<0. 05 ), and the tortuosity of the nerve fibers was significantly increased in the eye wearing SCL compared with control group. The densities of anterior stromal cells were lower while the microdot densities in the stroma were higher in SCL group than that in control group ( P<0.05 ) . The polymorphology of corneal endothelial cells was more obvious in SCL group, but the densities of endothelial cells were similar between two groups ( P>0.05). The SCL wearers showed a thinner thickness of central corneal epithelium than control group (P<0. 05).CONCLUSION: The corneal morphologic changes are more obvious with the longer time, and the changes is not ignored.
