国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2015年
5期
750-754
,共5页
Gowtham Jonna%Daniel B. Roth%Howard F. Fine%H. Matthew Wheatley%Jonathan L. Prenner%Arvin Kheterpal%Suzanne Cohen%William J. Feuer
Gowtham Jonna%Daniel B. Roth%Howard F. Fine%H. Matthew Wheatley%Jonathan L. Prenner%Arvin Kheterpal%Suzanne Cohen%William J. Feuer
Gowtham Jonna%Daniel B. Roth%Howard F. Fine%H. Matthew Wheatley%Jonathan L. Prenner%Arvin Kheterpal%Suzanne Cohen%William J. Feuer
玻璃体内注射部位%抗血管生长因子疗法%眼内炎
玻璃體內註射部位%抗血管生長因子療法%眼內炎
파리체내주사부위%항혈관생장인자요법%안내염
intravitreal injection site%anti - VEGF therapy%endophthalmitis
目的:探讨下方玻璃体腔注射比上方注射出现注射后眼内炎的几率是否更高。下方小梁切除术滤过泡眼内炎的发病率高于上方小梁切除术滤过泡,有可能是因为细菌聚集在下方的泪湖。<br> 方法:经过广泛实践过的眼内炎病例数据库验证,发现在2a的研究期间内,有5例眼内炎病例。同时,为了评估注射部位对发病率的影响,对治疗过的909例1121眼共计8672次注射进行了回顾性调查。<br> 结果:5眼出现感染性眼内炎,80%的眼内炎病例均是下方注射,尽管所选病例中84.6%是位于上方注射。与感染有关的下方注射部位的危险比是(OR)22.1(P=0.006)。<br> 结论:玻璃体腔注射后感染眼内炎的几率很小,仅为0.025%。避免在偏下象限进行玻璃体腔注射可能会进一步减小眼内炎的发病率。
目的:探討下方玻璃體腔註射比上方註射齣現註射後眼內炎的幾率是否更高。下方小樑切除術濾過泡眼內炎的髮病率高于上方小樑切除術濾過泡,有可能是因為細菌聚集在下方的淚湖。<br> 方法:經過廣汎實踐過的眼內炎病例數據庫驗證,髮現在2a的研究期間內,有5例眼內炎病例。同時,為瞭評估註射部位對髮病率的影響,對治療過的909例1121眼共計8672次註射進行瞭迴顧性調查。<br> 結果:5眼齣現感染性眼內炎,80%的眼內炎病例均是下方註射,儘管所選病例中84.6%是位于上方註射。與感染有關的下方註射部位的危險比是(OR)22.1(P=0.006)。<br> 結論:玻璃體腔註射後感染眼內炎的幾率很小,僅為0.025%。避免在偏下象限進行玻璃體腔註射可能會進一步減小眼內炎的髮病率。
목적:탐토하방파리체강주사비상방주사출현주사후안내염적궤솔시부경고。하방소량절제술려과포안내염적발병솔고우상방소량절제술려과포,유가능시인위세균취집재하방적루호。<br> 방법:경과엄범실천과적안내염병례수거고험증,발현재2a적연구기간내,유5례안내염병례。동시,위료평고주사부위대발병솔적영향,대치료과적909례1121안공계8672차주사진행료회고성조사。<br> 결과:5안출현감염성안내염,80%적안내염병례균시하방주사,진관소선병례중84.6%시위우상방주사。여감염유관적하방주사부위적위험비시(OR)22.1(P=0.006)。<br> 결론:파리체강주사후감염안내염적궤솔흔소,부위0.025%。피면재편하상한진행파리체강주사가능회진일보감소안내염적발병솔。
?AlM:To determine whether inferior injections had a higher incidence of post-injection endophthalmitis than superior injections. The incidence of endophthalmitis is higher for inferior than superior trabeculectomy filtering blebs, possibly due to bacteria pooling in the inferior tear lake. <br> ? METHODS: A practice - wide database of endophthalmitis cases identified 5 occurring during the two-year study period. A retrospective review of 8 672 injections in 1 121 eyes of 909 patients treated during the same two-year study period was performed in order to assess the injection site location. <br> ?RESULTS: Five eyes developed presumed infectious endophthalmitis. Eighty percent of endophthalmitis cases were injected inferiorly, even though 84. 6% of the total cohort was injected superiorly. The odds ratio of infection associated with inferior injection location is 22. 1 (P=0. 006). <br> ? CONCLUSlON: Endophthalmitis after intravitreal injection is rare, occurring in only 0. 025% of injections overall. Avoiding intravitreal injections in the inferior quadrants may further reduce the rate of endophthalmitis.