中国优生优育
中國優生優育
중국우생우육
CHINESE JOURNAL OF HEALTHY BIRTH & CHILD CARE
2014年
8期
551-554
,共4页
社区获得性肺炎%孕妇%可溶性髓细胞表达触发受体-1%C-反应蛋白%白介素8
社區穫得性肺炎%孕婦%可溶性髓細胞錶達觸髮受體-1%C-反應蛋白%白介素8
사구획득성폐염%잉부%가용성수세포표체촉발수체-1%C-반응단백%백개소8
目的 探讨本文患者相关血清指标与孕妇CAP病情轻重程度的关系.方法 将50例CAP孕妇分为非重症肺炎组(n=30)和重症肺炎组(n=20)进行分组研究;血清sTREM-1和CRP采用酶联免疫吸附法(ELISA)测定;IL-8水平测定采用放射免疫分析法(RIA).结果 CAP孕妇组8项临床常规检查指标均显著高于正常对照组(P均＜0.01).三项血清指标水平非重症CAP组显著高于正常对照组(P均＜0.05);而重症CAP组显著高于非重症CAP组(P均＜0.05).二项病情评分参数分值重症CAP组显著高于非重症CAP组(P均＜0.05).患者血清sTREM-1水平与八项指标阳性率比较均呈显著正相关(r=0.621,0.812,0.852,0.898,0.586,0.579,0.632,0.743,0.790,P均＜0.01). CRP水平与IL-8,WBC,NEU和阳性率呈微弱相关(r=0.445,0.457,0.451,0.520,P=0.047,0.045,0.049,0.051),余五项皆无显著相关性(P＞0.05).IL-8水平与八项指标阳性率比较与sTREM-1相似均呈显著正相关(r=0.879,0.731,0.807,0.594,0.538,0.652,0.701,0.718(P均＜0.05).结论 结果提示,sTREM-1水平的变化与CAP病情轻重程度关系一致,其测定对于孕妇CAP的早期诊断、治疗,保障优生和优育有重要意义.
目的 探討本文患者相關血清指標與孕婦CAP病情輕重程度的關繫.方法 將50例CAP孕婦分為非重癥肺炎組(n=30)和重癥肺炎組(n=20)進行分組研究;血清sTREM-1和CRP採用酶聯免疫吸附法(ELISA)測定;IL-8水平測定採用放射免疫分析法(RIA).結果 CAP孕婦組8項臨床常規檢查指標均顯著高于正常對照組(P均＜0.01).三項血清指標水平非重癥CAP組顯著高于正常對照組(P均＜0.05);而重癥CAP組顯著高于非重癥CAP組(P均＜0.05).二項病情評分參數分值重癥CAP組顯著高于非重癥CAP組(P均＜0.05).患者血清sTREM-1水平與八項指標暘性率比較均呈顯著正相關(r=0.621,0.812,0.852,0.898,0.586,0.579,0.632,0.743,0.790,P均＜0.01). CRP水平與IL-8,WBC,NEU和暘性率呈微弱相關(r=0.445,0.457,0.451,0.520,P=0.047,0.045,0.049,0.051),餘五項皆無顯著相關性(P＞0.05).IL-8水平與八項指標暘性率比較與sTREM-1相似均呈顯著正相關(r=0.879,0.731,0.807,0.594,0.538,0.652,0.701,0.718(P均＜0.05).結論 結果提示,sTREM-1水平的變化與CAP病情輕重程度關繫一緻,其測定對于孕婦CAP的早期診斷、治療,保障優生和優育有重要意義.
목적 탐토본문환자상관혈청지표여잉부CAP병정경중정도적관계.방법 장50례CAP잉부분위비중증폐염조(n=30)화중증폐염조(n=20)진행분조연구;혈청sTREM-1화CRP채용매련면역흡부법(ELISA)측정;IL-8수평측정채용방사면역분석법(RIA).결과 CAP잉부조8항림상상규검사지표균현저고우정상대조조(P균＜0.01).삼항혈청지표수평비중증CAP조현저고우정상대조조(P균＜0.05);이중증CAP조현저고우비중증CAP조(P균＜0.05).이항병정평분삼수분치중증CAP조현저고우비중증CAP조(P균＜0.05).환자혈청sTREM-1수평여팔항지표양성솔비교균정현저정상관(r=0.621,0.812,0.852,0.898,0.586,0.579,0.632,0.743,0.790,P균＜0.01). CRP수평여IL-8,WBC,NEU화양성솔정미약상관(r=0.445,0.457,0.451,0.520,P=0.047,0.045,0.049,0.051),여오항개무현저상관성(P＞0.05).IL-8수평여팔항지표양성솔비교여sTREM-1상사균정현저정상관(r=0.879,0.731,0.807,0.594,0.538,0.652,0.701,0.718(P균＜0.05).결론 결과제시,sTREM-1수평적변화여CAP병정경중정도관계일치,기측정대우잉부CAP적조기진단、치료,보장우생화우육유중요의의.
