CAJ | 학술논문

1例71岁男性患者胃癌术后行XELOX方案（第1天奥沙利铂200 mg静脉滴注；第2~15天卡培他滨1500 mg、2次／d口服）辅助化疗。口服卡培他滨首日当晚患者出现排尿起始延缓、尿线变细、射程缩短、尿后滴沥，并持续加重。查体见下腹隆起，叩诊浊音，急行肾功能检查未见异常。给予盐酸坦索罗辛0.2 mg口服，用药后约2 h患者排尿困难缓解，至次日晨6时累计排尿约600 ml。第2天起停用卡培他滨。出于自身病情考虑，患者于第4天上午再次自行口服卡培他滨1500 mg，约5 h后排尿困难症状复现。口服盐酸坦索罗辛0.2 mg后约2 h排尿困难缓解。停用卡培他滨，连续口服盐酸坦索罗辛12 d，患者未再出现排尿困难。
1례71세남성환자위암술후행XELOX방안（제1천오사리박200 mg정맥적주；제2~15천잡배타빈1500 mg、2차／d구복）보조화료。구복잡배타빈수일당만환자출현배뇨기시연완、뇨선변세、사정축단、뇨후적력，병지속가중。사체견하복륭기，고진탁음，급행신공능검사미견이상。급여염산탄색라신0.2 mg구복，용약후약2 h환자배뇨곤난완해，지차일신6시루계배뇨약600 ml。제2천기정용잡배타빈。출우자신병정고필，환자우제4천상오재차자행구복잡배타빈1500 mg，약5 h후배뇨곤난증상복현。구복염산탄색라신0.2 mg후약2 h배뇨곤난완해。정용잡배타빈，련속구복염산탄색라신12 d，환자미재출현배뇨곤난。
A 71-year-old male patient with gastric cancer received adjuvant chemotherapy with XELOX( intravenous infusion of oxaliplatin 200 mg on the first day and oral capecitabine 1 500 mg twice daily on day 2-15). During the first night after the capecitabine was taken,he developed dysuria. The major clinical manifestations were urination delaying,weak steam of urine,short distance of micturition and trickle micturition,and the symptoms exacerbated continuously. Physical examination findings were lower abdomen bulging,dullness to percussion, and there were no abnormality in the renal function. Tamsulosin hydrochloride 0. 2 mg was given. The symptoms of dysuria relieved after 2 hours. The cumulative amount of urine was 600 ml by 6 :00 am on the next day. Capecitabine was suspended. On the fourth day,the patient self-medicated with capecitabine 1 500 mg again due to his condition and the dysuria recurred after 5 hours. The symptom was relieved when tamsulosin hydrochloride 0. 2 mg was given. So capecitabine was stopped and with the treatment with tamsulosin hydrochloride for 12 days,the dysuria didn't recur.