CAJ | 학술논문

目的：探讨血必净注射液在治疗感染性休克的效果及对血清降钙素原（ PCT）及CRP水平的影响。方法选取2013年4月～2014年10月我院收治的252例感染性休克作为研究对象，将患者随机分为研究组和对照组，各126例。对照组患者使用常规治疗，观察组患者在常规治疗基础上使用血必净静脉滴注治疗。综合比较两组患者治疗总有效率、治疗前后血清PCT、CRP值及不良反应发生率的差异。结果研究组治疗总有效率为89．7％，显著高于对照组的78．6％（P＜0．05）；治疗后研究组患者血清PCT、CRP值均显著优于对照组（P＜0．05）；两组均无严重不良反应（ P＞0．05）。结论血必净注射液治疗感染性休克疗效确切，可显著降低血清PCT、CRP水平，无严重不良反应。
목적：탐토혈필정주사액재치료감염성휴극적효과급대혈청강개소원（ PCT）급CRP수평적영향。방법선취2013년4월～2014년10월아원수치적252례감염성휴극작위연구대상，장환자수궤분위연구조화대조조，각126례。대조조환자사용상규치료，관찰조환자재상규치료기출상사용혈필정정맥적주치료。종합비교량조환자치료총유효솔、치료전후혈청PCT、CRP치급불량반응발생솔적차이。결과연구조치료총유효솔위89．7％，현저고우대조조적78．6％（P＜0．05）；치료후연구조환자혈청PCT、CRP치균현저우우대조조（P＜0．05）；량조균무엄중불량반응（ P＞0．05）。결론혈필정주사액치료감염성휴극료효학절，가현저강저혈청PCT、CRP수평，무엄중불량반응。
ABSTRACT:OBJECTIVE To investigate effects of Xuebijing injection for the treatment of septic shock and the influenceofPCTandCRPlevels.METHODS 126casesofsepticshockpatientsinourhospitalwererandomlydi-vided into research group and control group,each were 63 cases.Research group were treated with Xuebijing intrave-nous injection treatment based on conventional therapy.Control group were treated with conventional therapy on-ly.Total effective rate,PCT and CPR before and after treatment,adverse reaction rate were compared.RESULTS The total effective rate of research group were 89.7%,which was higher than control group.The PCT and CRP of re-search group after treatment were better than control group ( P<0.05).There was no serious adverse reaction in the? 84? <br> two groups (P>0.05).CONCLUSION Xuebijing has exact effect for septic shock.It can reduce PCT and CRP levels significantly and has no serious adverse reaction.