CAJ | 학술논문

目的：探讨替罗非班联合主动脉球囊反搏对于行PCI术后冠脉复杂病变患者的心率、低血压、休克及各种并发症发生情况的影响，观察其疗效。方法：选取冠脉复杂病变患者80例，先进行主动脉球囊反搏泵植入，再进行PCI术治疗，再随机分组给予替罗非班治疗。观察两组患者采用不同介入治疗方法之后，血栓形成情况等施药后临床反应以及心绞痛、心衰、心肌梗塞复发、急性或亚急性支架内血栓、死亡等各种并发症发生情况。结果：在施药后的临床反应方面，进行血栓评分比较，观察组PCI术后血栓评分为2.2±0.4，采用替罗非班联合主动脉球囊反搏之后血栓评分为0.1±0.1，对照组PCI术后血栓评分为2.0±0.5,进行主动脉球囊反搏治疗后，血栓评分为0.5±0.2。在出院后心血管事件发生情况调差方面，观察组发生心率失常及心绞痛有1例，无低血糖及休克、心肌梗塞及心绞痛、死亡。对照组发生心率失常及心绞痛、低血糖及休克、心肌梗塞及心衰、死亡分别有6例、3例、3例、1例。结论：在行PCI术后冠脉复杂病变的治疗过程中，采用替罗非班联合主动脉球囊反搏介入治疗能有效提高临床治疗效果，降低血栓形成，大大减少并发症的发生，减少死亡率，在一定程度上减轻患者的痛苦。
목적：탐토체라비반연합주동맥구낭반박대우행PCI술후관맥복잡병변환자적심솔、저혈압、휴극급각충병발증발생정황적영향，관찰기료효。방법：선취관맥복잡병변환자80례，선진행주동맥구낭반박빙식입，재진행PCI술치료，재수궤분조급여체라비반치료。관찰량조환자채용불동개입치료방법지후，혈전형성정황등시약후림상반응이급심교통、심쇠、심기경새복발、급성혹아급성지가내혈전、사망등각충병발증발생정황。결과：재시약후적림상반응방면，진행혈전평분비교，관찰조PCI술후혈전평분위2.2±0.4，채용체라비반연합주동맥구낭반박지후혈전평분위0.1±0.1，대조조PCI술후혈전평분위2.0±0.5,진행주동맥구낭반박치료후，혈전평분위0.5±0.2。재출원후심혈관사건발생정황조차방면，관찰조발생심솔실상급심교통유1례，무저혈당급휴극、심기경새급심교통、사망。대조조발생심솔실상급심교통、저혈당급휴극、심기경새급심쇠、사망분별유6례、3례、3례、1례。결론：재행PCI술후관맥복잡병변적치료과정중，채용체라비반연합주동맥구낭반박개입치료능유효제고림상치료효과，강저혈전형성，대대감소병발증적발생，감소사망솔，재일정정도상감경환자적통고。
ObjectiveTo study curative effect on the complex coronary artery lesions patients after the PCI surgery tirofiban Hydrochloride and aortic balloon counterpulsation.Methods Choose 80 patients with complex coronary artery lesions in patients, to PCI, then respectively for class had joint aortic balloon counterpulsation with pure aortic balloon counterpulsation interventional treatment. After observing two groups of patients with different intervention methods, thrombosis after applying pesticide such as clinical response and recurrence of angina pectoris, heart failure, myocardial infarction, acute or subacute stent thrombosis, death and other complications.Results In the aspect of clinical response after applying pesticide, thrombus score comparison, observation group of PCI postoperative thrombosis score was2.2±0.4, use for class after aortic balloon counterpulsation thrombosis had score was 0.1±0.1, the control PCI postoperative thrombosis score was 2.0±0.5, for aortic balloon counterpulsation treatment, blood clots score was 0.5±0.2. In the conditions controlled cardiovascular events after discharge, observe group arrhythmia and 1 case of angina pectoris, hypoglycemia and shock, myocardial infarction and angina pectoris, death. Control arrhythmia, angina pectoris, hypoglycemia and shock, myocardial infarction and heart failure, there were 6 cases died, 3 cases, 3 cases, 1 case.Conclusion In the treatment of PCI postoperative complex coronary artery lesions in the process of using for class had joint aortic balloon counterpulsation interventional therapy can effectively improve the clinical curative effect, reduce thrombosis, greatly reduce the occurrence of complications and reduce mortality rate, in a certain extent, ease the pain of the patients.