CAJ | 학술논문

目的：运用Meta分析法综合评估急性结石性胆囊炎行腹腔镜胆囊切除手术的时机选择。方法：收集1991-2013年国内、外有关中国人群急性结石性胆囊炎腹腔镜胆囊切除术手术时机的研究文献，采用Meta分析的随机效应模型，计算有关手术时机与手术并发症、中转开腹率的OR值及95%CI。结果：共筛选出23篇相关文献。分析发现，与延期（发病超过72 h）相比，早期（发病72 h内）行腹腔镜胆囊切除术可以降低并发症发生率（OR=0.47，95%CI=0.35～0.62，P＜0.001）和中转开腹率（OR=0.27，95%CI=0.20～0.37， P＜0.001）。结论：发病后72 h内行腹腔镜胆囊切除术将显著降低出现并发症和中转开腹的风险。
목적：운용Meta분석법종합평고급성결석성담낭염행복강경담낭절제수술적시궤선택。방법：수집1991-2013년국내、외유관중국인군급성결석성담낭염복강경담낭절제술수술시궤적연구문헌，채용Meta분석적수궤효응모형，계산유관수술시궤여수술병발증、중전개복솔적OR치급95%CI。결과：공사선출23편상관문헌。분석발현，여연기（발병초과72 h）상비，조기（발병72 h내）행복강경담낭절제술가이강저병발증발생솔（OR=0.47，95%CI=0.35～0.62，P＜0.001）화중전개복솔（OR=0.27，95%CI=0.20～0.37， P＜0.001）。결론：발병후72 h내행복강경담낭절제술장현저강저출현병발증화중전개복적풍험。
Objective:To evaluate the effects of different optional time leading to complication and con-version to laparotomy by laparoscopic cholecystectomy in acute calculous cholecystitis. Methods:Search all of domestic and international research literatures on different optional time by laparoscopic cholecystectomy about the Chinese from 1991 to 2013. The random effects model was selected for conducting the meta-analysis, to calculate the OR and 95%CI of different optional time leading to complication and conversion to laparotomy. Results:Overall 23 articles were eligible and were included into the meta-analysis, There was signiifcant statisti-cal difference in complication (OR=0.47, 95%CI=0.35~0.62, P<0.001) and conversion to laparotomy (OR=0.27, 95%CI=0.20~0.37, P<0.001) between the<72 h group and>72 h group. Conclusion:Meta-analysis shows that in the laparoscopic cholecystectomy progress, the surgical outcome is best within 72 h, which can reduce the complication and decline the conversion.