医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2015年
2期
12-13
,共2页
全膝关节置换术%静脉血栓%口服抗凝药物
全膝關節置換術%靜脈血栓%口服抗凝藥物
전슬관절치환술%정맥혈전%구복항응약물
Total knee replacement%Vein thrombosis%Oral anticoagulant drugs
全膝关节表面置换术（totalkneearthroplasty，TKA）因手术创伤大等原因，术后深静脉血栓的形成和肺栓塞成为其严重并发症，导致脑梗死、心肌梗死等严重不良事件的发生。因此，TKA术后预防静脉血栓栓塞病（venousthromboembolism，VTE）的发生十分必要。本文以目前新型口服抗凝药物如阿哌沙班等对TKA术后VTE预防的效用性和安全性做一综述，为指导TKA术后抗凝治疗方案的选择提供参考。
全膝關節錶麵置換術（totalkneearthroplasty，TKA）因手術創傷大等原因，術後深靜脈血栓的形成和肺栓塞成為其嚴重併髮癥，導緻腦梗死、心肌梗死等嚴重不良事件的髮生。因此，TKA術後預防靜脈血栓栓塞病（venousthromboembolism，VTE）的髮生十分必要。本文以目前新型口服抗凝藥物如阿哌沙班等對TKA術後VTE預防的效用性和安全性做一綜述，為指導TKA術後抗凝治療方案的選擇提供參攷。
전슬관절표면치환술（totalkneearthroplasty，TKA）인수술창상대등원인，술후심정맥혈전적형성화폐전새성위기엄중병발증，도치뇌경사、심기경사등엄중불량사건적발생。인차，TKA술후예방정맥혈전전새병（venousthromboembolism，VTE）적발생십분필요。본문이목전신형구복항응약물여아고사반등대TKA술후VTE예방적효용성화안전성주일종술，위지도TKA술후항응치료방안적선택제공삼고。
Total knee arthroplasty (total knee arthroplasty, TKA) by surgical trauma and other reasons, the formation of postoperative deep vein thrombosis and pulmonary embolism as its serious complications, leading to cerebral infarction, myocardial infarction, such as the occurrence of serious adverse events. TKA surgery, therefore, the prevention of venous thromboembolic disease (venous thromboembolism, VTE) is necessary. Based on the new type of oral anticoagulant drugs such as pp shaaban o on postoperative VTE prevention effect and safety of TKA do a review, to guide the choice of TKA postoperative anticoagulation therapy to provide the reference.
