温州医科大学学报
溫州醫科大學學報
온주의과대학학보
Journal of Wenzhou Medical University
2015年
4期
248-251
,共4页
陈慧君%黄亦波%林蓉蓉%郑飞云
陳慧君%黃亦波%林蓉蓉%鄭飛雲
진혜군%황역파%림용용%정비운
宫颈肿瘤%盆腔淋巴结转移%肿瘤大小%宫旁浸润%回归分析
宮頸腫瘤%盆腔淋巴結轉移%腫瘤大小%宮徬浸潤%迴歸分析
궁경종류%분강림파결전이%종류대소%궁방침윤%회귀분석
uterine cervical neoplasms%pelvic lymph node metastasis%tumor size%parametrial invasion:regression analysis
目的:分析IB~IIB期宫颈癌盆腔淋巴结转移情况及相关高危因素,为早期宫颈癌的手术方式提供参考。方法:对158例进行广泛性全子宫切除术联合盆腔淋巴结清扫的IB~IIB期宫颈癌患者的临床病理资料进行回顾性分析,对影响淋巴结转移的因素采用logistic回归分析。结果:158例IB~IIB期宫颈癌有36例淋巴结转移阳性,转移率为22.8%,其中闭孔淋巴结转移22例(占13.9%),髂内淋巴结转移15例(占9.5%),髂外淋巴结转移10例(占6.3%),髂总淋巴结转移7例(占4.4%),腹股沟深淋巴结转移4例(占2.5%),宫旁淋巴结转移1例(占0.6%),腹主动脉旁淋巴结转移1例(占0.6%)。21例孤立淋巴结阳性,15例多组淋巴结阳性。单因素分析结果显示肿瘤直径大小超过4 cm,术前鳞状细胞癌抗原(SCC-Ag)及宫旁浸润与盆腔淋巴结转移相关(P<0.05)。logistic回归分析结果显示肿瘤直径超过4 cm及宫旁浸润是盆腔淋巴结转移的独立危险因素(P<0.05)。结论:IB~IIB期宫颈癌盆腔淋巴结转以闭孔淋巴结最易受累,肿瘤直径超过4 cm及宫旁浸润是盆腔淋巴结转移的高危因素。
目的:分析IB~IIB期宮頸癌盆腔淋巴結轉移情況及相關高危因素,為早期宮頸癌的手術方式提供參攷。方法:對158例進行廣汎性全子宮切除術聯閤盆腔淋巴結清掃的IB~IIB期宮頸癌患者的臨床病理資料進行迴顧性分析,對影響淋巴結轉移的因素採用logistic迴歸分析。結果:158例IB~IIB期宮頸癌有36例淋巴結轉移暘性,轉移率為22.8%,其中閉孔淋巴結轉移22例(佔13.9%),髂內淋巴結轉移15例(佔9.5%),髂外淋巴結轉移10例(佔6.3%),髂總淋巴結轉移7例(佔4.4%),腹股溝深淋巴結轉移4例(佔2.5%),宮徬淋巴結轉移1例(佔0.6%),腹主動脈徬淋巴結轉移1例(佔0.6%)。21例孤立淋巴結暘性,15例多組淋巴結暘性。單因素分析結果顯示腫瘤直徑大小超過4 cm,術前鱗狀細胞癌抗原(SCC-Ag)及宮徬浸潤與盆腔淋巴結轉移相關(P<0.05)。logistic迴歸分析結果顯示腫瘤直徑超過4 cm及宮徬浸潤是盆腔淋巴結轉移的獨立危險因素(P<0.05)。結論:IB~IIB期宮頸癌盆腔淋巴結轉以閉孔淋巴結最易受纍,腫瘤直徑超過4 cm及宮徬浸潤是盆腔淋巴結轉移的高危因素。
목적:분석IB~IIB기궁경암분강림파결전이정황급상관고위인소,위조기궁경암적수술방식제공삼고。방법:대158례진행엄범성전자궁절제술연합분강림파결청소적IB~IIB기궁경암환자적림상병리자료진행회고성분석,대영향림파결전이적인소채용logistic회귀분석。결과:158례IB~IIB기궁경암유36례림파결전이양성,전이솔위22.8%,기중폐공림파결전이22례(점13.9%),가내림파결전이15례(점9.5%),가외림파결전이10례(점6.3%),가총림파결전이7례(점4.4%),복고구심림파결전이4례(점2.5%),궁방림파결전이1례(점0.6%),복주동맥방림파결전이1례(점0.6%)。21례고립림파결양성,15례다조림파결양성。단인소분석결과현시종류직경대소초과4 cm,술전린상세포암항원(SCC-Ag)급궁방침윤여분강림파결전이상관(P<0.05)。logistic회귀분석결과현시종류직경초과4 cm급궁방침윤시분강림파결전이적독립위험인소(P<0.05)。결론:IB~IIB기궁경암분강림파결전이폐공림파결최역수루,종류직경초과4 cm급궁방침윤시분강림파결전이적고위인소。
Objective:To analysis the factors affecting lymph node metastasis in stage IB1 to IIB uterine cervical cancer. Methods:A total of 158 patients with stage IB to IIB cervical carcinomas treated with radical hysterectomy and systematic pelvic lymphadenectomy were retrospectively analyzed. The logistic multivariate analysis was used to select independent high-risk factors. Results:Thirty-six (22.8%) patients had pelvic lymph node metastasis. Of 36 lymph node metastases, 22 were in the obturator, 15 in the internal iliac, 10 in the external iliac, 7 in the common iliac, 4 in the deep inguinal, 1 in the parametrial iliac and 1 in the para aortic. Univari-ate analysis revealed that tumor size, preoperative SCC-Ag level and parametrial invasion were related to pelvic lymph node metastasis. Multivariate analysis revealed that tumor size greater than 4 cm and parametrial invasion were independently associated with nodal metastasis. Conclusion:The obturator lymph nodes are most frequent-ly involved in stage IB~IIB uterine cervical cancer. Tumor size greater than 4 cm and parametrial invasion are high-risk factors of pelvic lymph node metastasis.