CAJ | 학술논문

目的：制定本地区不同妊娠时期胱抑素C（CysC）的参考范围。方法：选取妊娠妇女360例，妊娠早期、中期、晚期分三组，各120例，检测妊娠妇女血清CysC水平，统计分析差异，参照CLSI C28-A2文件提供的方法建立妊娠时期CysC参考范围。结果：三组测定结果间存在统计学差异（P＜0.01），妊娠时期CysC参考范围：早期为0.58～0.96mg/L，中期为0.81～1.37mg/L,晚期为1.19～1.80mg/L。结论：孕妇血清CysC水平随着妊娠时间的增加而升高，实验室有必要对妊娠期妇女建立正常的参考范围。
목적：제정본지구불동임신시기광억소C（CysC）적삼고범위。방법：선취임신부녀360례，임신조기、중기、만기분삼조，각120례，검측임신부녀혈청CysC수평，통계분석차이，삼조CLSI C28-A2문건제공적방법건립임신시기CysC삼고범위。결과：삼조측정결과간존재통계학차이（P＜0.01），임신시기CysC삼고범위：조기위0.58～0.96mg/L，중기위0.81～1.37mg/L,만기위1.19～1.80mg/L。결론：잉부혈청CysC수평수착임신시간적증가이승고，실험실유필요대임신기부녀건립정상적삼고범위。
Objective: To develop the local area of different gestational age of cystatin C (CysC) of the reference range.Methods:Select 360 cases of pregnant women, early pregnancy, mid, late stage were divided into three groups, each 120 cases of pregnant women, the detection of serum CysC level, differences in statistical analysis, referring to the method of CLSI C28-A2 ifle that provides a CysC reference range established during the period of pregnancy.Results:There was statistical difference between the determination results of three groups (P<0.01), the period of CysC reference range: early pregnancy 0.58~0.96 mg/L, for the medium-term 0.81~1.37 mg/L, 1.19~1.80 late for mg/L.Conclusion:Serum CysC level in pregnant women with increasing gestational duration increased, it is necessary to establish the reference range of normal laboratory for pregnant women.