中国药物应用与监测
中國藥物應用與鑑測
중국약물응용여감측
CHINESE JOURNAL OF DRUG APPLICATION AND MONITORING
2015年
2期
127-128
,共2页
廖敏辉%李平%刘永刚%李剑芳
廖敏輝%李平%劉永剛%李劍芳
료민휘%리평%류영강%리검방
环孢素A%地尔硫卓%狼疮肾炎%嘴唇水肿%呕吐
環孢素A%地爾硫卓%狼瘡腎炎%嘴脣水腫%嘔吐
배포소A%지이류탁%랑창신염%취진수종%구토
Cyclosporine A%Diltiazem%Lupus nephritis%Lip edema%Vomiting
1例15岁男性患者因反复浮肿伴皮疹住院,既往有狼疮肾炎2年余。入院前使用激素和吗替麦考酚酯治疗,狼疮肾炎控制效果不佳,不良反应明显。入院后停用激素,改用环孢素联合地尔硫卓治疗,患者出现嘴唇水肿、呕吐、发热等不良反应。停用两药后对症治疗,明显好转,5d后恢复正常,1周后给予他克莫司胶囊未出现类似症状。
1例15歲男性患者因反複浮腫伴皮疹住院,既往有狼瘡腎炎2年餘。入院前使用激素和嗎替麥攷酚酯治療,狼瘡腎炎控製效果不佳,不良反應明顯。入院後停用激素,改用環孢素聯閤地爾硫卓治療,患者齣現嘴脣水腫、嘔吐、髮熱等不良反應。停用兩藥後對癥治療,明顯好轉,5d後恢複正常,1週後給予他剋莫司膠囊未齣現類似癥狀。
1례15세남성환자인반복부종반피진주원,기왕유랑창신염2년여。입원전사용격소화마체맥고분지치료,랑창신염공제효과불가,불량반응명현。입원후정용격소,개용배포소연합지이류탁치료,환자출현취진수종、구토、발열등불량반응。정용량약후대증치료,명현호전,5d후회복정상,1주후급여타극막사효낭미출현유사증상。
One 15-year-old male patient with recurrent rash and swelling was admitted in hospital, with a history of lupus nephritis for more than 2 years. Glucocorticoids and mycophenolate mofetil were given before admission, lupus nephritis was not controlled well and adverse reactions happened. Steroid was replaced by cyclosporine and diltiazem after admission. Lip edema, vomiting and fever appeared and these two drugs were discontinued. The symptom signiifcantly improved after symptomatic treatment. Five days later, situation returned to normal. A week later, tacrolimus capsules were administrated and no similar symptoms occurred.