医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2015年
16期
183-183
,共1页
雷贝拉唑%曲美布汀%功能性消化不良
雷貝拉唑%麯美佈汀%功能性消化不良
뢰패랍서%곡미포정%공능성소화불량
Rabeprazole%Trimebutin%Functional dyspepsia
目的：观察雷贝拉唑联合曲美布汀治疗功能性消化不良临床疗效。方法200例功能性消化不良患者随机分为两组，分别为观察组88例，对照组112例。两组患者均每日早餐前服用1次雷贝拉唑肠溶胶囊，20mg/次；观察组患者每日三餐后加服曲美布汀，0.1g/次,疗程2w。结果观察组上腹痛、上腹灼烧感、餐后饱胀症状改善情况明显优于对照组(<0.01)；嗳气症状改善情况无统计学意义(跃0.05)。对照组总有效率为74.1%；观察组总有效率为79.5%。两组均未出现明显不良反应。结论雷贝拉唑与曲美布汀联用可明显改善功能性消化不良的症状，且较为安全。
目的：觀察雷貝拉唑聯閤麯美佈汀治療功能性消化不良臨床療效。方法200例功能性消化不良患者隨機分為兩組，分彆為觀察組88例，對照組112例。兩組患者均每日早餐前服用1次雷貝拉唑腸溶膠囊，20mg/次；觀察組患者每日三餐後加服麯美佈汀，0.1g/次,療程2w。結果觀察組上腹痛、上腹灼燒感、餐後飽脹癥狀改善情況明顯優于對照組(<0.01)；噯氣癥狀改善情況無統計學意義(躍0.05)。對照組總有效率為74.1%；觀察組總有效率為79.5%。兩組均未齣現明顯不良反應。結論雷貝拉唑與麯美佈汀聯用可明顯改善功能性消化不良的癥狀，且較為安全。
목적：관찰뢰패랍서연합곡미포정치료공능성소화불량림상료효。방법200례공능성소화불량환자수궤분위량조，분별위관찰조88례，대조조112례。량조환자균매일조찬전복용1차뢰패랍서장용효낭，20mg/차；관찰조환자매일삼찬후가복곡미포정，0.1g/차,료정2w。결과관찰조상복통、상복작소감、찬후포창증상개선정황명현우우대조조(<0.01)；애기증상개선정황무통계학의의(약0.05)。대조조총유효솔위74.1%；관찰조총유효솔위79.5%。량조균미출현명현불량반응。결론뢰패랍서여곡미포정련용가명현개선공능성소화불량적증상，차교위안전。
Objective To observe the curative ef ect of combined therapy of rabeprazole and trimebutin for functional dyspepsia. Methods 200 patients with functional dyspepsia were randomly grouped into observation group (n=88)and controls group (n=112).The patients in the two groups were given rabeprazole sodium enteric-coated capsules 20mg 1 times a day before breakfast for 2 weeks , The patients in the observation group were given trimebutin 0.1g 3 times a day after meals in addition to rabeprazole for 2 weeks.Results The symptoms of upper abdominal pain, stomach burn , abdominal distention after meals in the patients in the observation group were more improved than in the control group( <0.01) except for eructation.The total ef ective rate of the control group was 74.1%,The total ef ective rate of the observation group was79.5%,No severe untoward ef ects were found in the both groups.Conclusion Combined therapy of rabeprazole and trimebutin is safe and ef ective for improving symptoms in functional dyspepsia.
