CAJ | 학술논문

目的：研究观察莫沙比利联合瑞巴派特与单用莫沙比利治疗慢性萎缩性胃炎的治疗效果比较。方法对我院2011年6月～2013年12月期间收治的慢性萎缩性胃炎病例进行研究，包括门诊和住院经病理确诊的245例。将这些病例按随机数表的方法随机分为两组，观察组给予莫沙比利联合瑞巴派特进行治疗，对照组给予莫沙比利治疗。对比观察观察组和对照组患者的治疗有效率和幽门螺杆菌的根除率。结果观察组使用莫沙比利联合瑞巴派特治疗慢性萎缩性胃炎的临床有效率和幽门螺杆菌的根除率明显高于对照组，其差异均有统计学意义（P<0.05）。结论莫沙比利联合瑞巴派特治疗慢性萎缩性胃炎相比于单纯使用莫沙比利具有更加明显的临床效果，可有效减少幽门螺杆菌的感染率而降低复发风险。
목적：연구관찰막사비리연합서파파특여단용막사비리치료만성위축성위염적치료효과비교。방법대아원2011년6월～2013년12월기간수치적만성위축성위염병례진행연구，포괄문진화주원경병리학진적245례。장저사병례안수궤수표적방법수궤분위량조，관찰조급여막사비리연합서파파특진행치료，대조조급여막사비리치료。대비관찰관찰조화대조조환자적치료유효솔화유문라간균적근제솔。결과관찰조사용막사비리연합서파파특치료만성위축성위염적림상유효솔화유문라간균적근제솔명현고우대조조，기차이균유통계학의의（P<0.05）。결론막사비리연합서파파특치료만성위축성위염상비우단순사용막사비리구유경가명현적림상효과，가유효감소유문라간균적감염솔이강저복발풍험。
Objec tive Discuss the clinical therapeutic of Mosapride combined with Rebamipide on the treatment of chronic atrophic gastritis Methods Choose our hospital treatments of 245 cases of patients with chronic atrophic gastritis, randomly divided into observation group and control group, observation group adopts the Mosapride combined with Rebamipide therapy treatment, con-trol group with Mosapride treatment, observe the clinical therapeutic effect of two groups and the status of helicobacter pylori eradication.Results The clinical therapeutic effect and Helicobacter py-lori eradication efficiency ratio of observation group was significantly higher than the control group, the differences were statistically significant (P<0.05). Conclusions Mosapride combined with Re-bamipide treatment of chronic atrophic gastritis are more obvious clinical effects compared with simply using Mosapride, which can effectively reduce the prevalence of H. pylori and reduces the risk of recurrence.