CAJ | 학술논문

目的：探讨超声弹性成像应变率比值法在鉴别乳腺肿瘤良恶性的价值。方法通过应用超声弹性成像应变率比值法，回顾分析2011年9月～2014年9月216例在我院检出并经病理证实的268个乳腺肿块，获得乳腺肿块与同深度周围组织的应变率比值，并采用ROC曲线分析鉴别乳腺良恶性的最佳诊断界点。结果恶性肿瘤的应变率比值（SR值）（4．9±2．94）显著大于良性肿瘤（1．80±1．11），差异有统计学意义（t＝2．257，P＝0．000）。超声弹性成像比值法对乳腺病灶的最佳诊断界点3．10，其ROC曲线下面积为0．976，其敏感性、特异性及准确性分别为92．2％、98．5％和97．7％。结论对比乳腺肿块与周围组织的硬度，可以更为准确、客观的判断乳腺肿物的良恶性，为临床诊断乳腺癌提供更有价值的量化指标。
목적：탐토초성탄성성상응변솔비치법재감별유선종류량악성적개치。방법통과응용초성탄성성상응변솔비치법，회고분석2011년9월～2014년9월216례재아원검출병경병리증실적268개유선종괴，획득유선종괴여동심도주위조직적응변솔비치，병채용ROC곡선분석감별유선량악성적최가진단계점。결과악성종류적응변솔비치（SR치）（4．9±2．94）현저대우량성종류（1．80±1．11），차이유통계학의의（t＝2．257，P＝0．000）。초성탄성성상비치법대유선병조적최가진단계점3．10，기ROC곡선하면적위0．976，기민감성、특이성급준학성분별위92．2％、98．5％화97．7％。결론대비유선종괴여주위조직적경도，가이경위준학、객관적판단유선종물적량악성，위림상진단유선암제공경유개치적양화지표。
Objective To evaluate the stiffness of breast lesions and explore its diagnostic value in differentiating malignant and benign breast lesions. Methods The ultrasound elastography strain rate(SR) ratio of 268 breast lesions detected and confirmed by pathology from 2011-9 to 2014-9 in our station were retrospective analyzed. .The SR ratio of breast lesions and the same depth of the surrounding tissue were summarized and the best cutoff point of UE strain ratios to differentiate benign and malignant was got by ROC curve analysis. Results The strain ratio value of malignant breast tumors (4.9±2.94) were significantly higher than benign ones (1.80±1.11). The difference was statistically significant (t=2.257, P=0.000). 3.10 was the best cutoff point of UE strain ratio for differentiating malignant and benign breast lesions. The AUC, sensitivity, specificity and accuracy were 0.976, 92.2%, 98.5%and 97.7%. Conclusion Comparing the stiffness of breast tumor and surrounding tissues, it is a more accurate, objective judgment to diagnose benign or malignant breast tumor, and a more valuable quantitative index for diagnosing breast tumor.