中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2015年
2期
141-143
,共3页
肾上腺素能α激动剂%谵妄
腎上腺素能α激動劑%譫妄
신상선소능α격동제%섬망
Adrenergic alpha-agonists%Delirium
目的 观察右美托咪定辅助麻醉对老年重症患者术后谵妄发生情况的影响. 方法 选择2014年1-10月于我院择期行腹部手术治疗的67例老年重症患者为研究对象,随机分为观察组35例和对照组32例,观察组持续静脉滴注右美托咪定,负荷剂量1 μg/kg,维持剂量0.2 μg·kg-1·h-1;对照组静脉滴注同体积的生理盐水替代.观察两组患者拔管时间、苏醒时间和谵妄发生情况. 结果 观察组苏醒时间和拔管时间分别为(18.4±6.9)min和(25.8±7.3)min,均早于对照组(24.6±7.4)min和(31.2±9.1)min,差异有统计学意义(t=4.626、3.494,均P＜0.001);观察组患者谵妄发生率8.6％(3/35),明显低于对照组28.1％(9/32)(x2=7.063,P=0.008). 结论 右美托咪定辅助麻醉可明显缩短老年重症患者苏醒时间和拔管时间,还可降低患者术后谵妄的发生率.
目的 觀察右美託咪定輔助痳醉對老年重癥患者術後譫妄髮生情況的影響. 方法 選擇2014年1-10月于我院擇期行腹部手術治療的67例老年重癥患者為研究對象,隨機分為觀察組35例和對照組32例,觀察組持續靜脈滴註右美託咪定,負荷劑量1 μg/kg,維持劑量0.2 μg·kg-1·h-1;對照組靜脈滴註同體積的生理鹽水替代.觀察兩組患者拔管時間、囌醒時間和譫妄髮生情況. 結果 觀察組囌醒時間和拔管時間分彆為(18.4±6.9)min和(25.8±7.3)min,均早于對照組(24.6±7.4)min和(31.2±9.1)min,差異有統計學意義(t=4.626、3.494,均P＜0.001);觀察組患者譫妄髮生率8.6％(3/35),明顯低于對照組28.1％(9/32)(x2=7.063,P=0.008). 結論 右美託咪定輔助痳醉可明顯縮短老年重癥患者囌醒時間和拔管時間,還可降低患者術後譫妄的髮生率.
목적 관찰우미탁미정보조마취대노년중증환자술후섬망발생정황적영향. 방법 선택2014년1-10월우아원택기행복부수술치료적67례노년중증환자위연구대상,수궤분위관찰조35례화대조조32례,관찰조지속정맥적주우미탁미정,부하제량1 μg/kg,유지제량0.2 μg·kg-1·h-1;대조조정맥적주동체적적생리염수체대.관찰량조환자발관시간、소성시간화섬망발생정황. 결과 관찰조소성시간화발관시간분별위(18.4±6.9)min화(25.8±7.3)min,균조우대조조(24.6±7.4)min화(31.2±9.1)min,차이유통계학의의(t=4.626、3.494,균P＜0.001);관찰조환자섬망발생솔8.6％(3/35),명현저우대조조28.1％(9/32)(x2=7.063,P=0.008). 결론 우미탁미정보조마취가명현축단노년중증환자소성시간화발관시간,환가강저환자술후섬망적발생솔.
Objective To observe the effect of dexmedetomidine anesthesia on postoperative delirium in elderly patients with severe diseases.Methods 67 elderly patients undergoing abdominal operation in our hospital from Jan.2014 to Oct.2014 were chosen as the research subjects,and randomly divided into the observation group (n =35) and the control group (n =32).In the observation group,35 cases were treated with dexmedetomidine in loading dose of 1 μg/kg and maintenance dose of 0.2 μg/kg.In the control group,32 cases were treated with the equal volume of saline instead of dexmedetomidine.The extubation time,recovery time and incidence of delirium were observed.Results The recovery time and extubation time were shorter in observation group than in control group[(18.4±6.9) min vs.(24.6± 7.4) min,(25.8 ±7.3) vs.(31.2±9.1) min,t=4.626,3.494,both P＜0.001].The incidence rate of postoperative delirium was lower in observation group much than in the control group (8.6％ vs.28.1％,x2 =7.063,P=0.008).Conclusions Dexmedetomidine anesthesia can significantly shorten the recovery time and extubation time,and reduce the incidence rate of postoperative delirium in elderly patients with severe diseases.
