CAJ | 학술논문

目的：观察醒脑静联合果糖、纳洛酮在治疗急性重度酒精中毒中的效果。方法选择我院2013年9月～2014年9月123例急性重度酒精中毒患者，根据收治顺位分为两组：单数61例患者为对照组，给予纳洛酮+生理盐水联合治疗，双数62例患者在对照组基础上加用醒脑静注射液，并将纳洛酮组的溶剂生理盐水改为果糖注射液，观察两组救治效果。结果观察组共济失调期患者恢复清醒时间和症状消失时间分别为（74.8±20.4）min、（264.5±50.6）min，昏睡期患者恢复清醒时间和症状消失时间分别为（153.4±36.7）min、（420.7±102.8）min，均短于对照组，急救总有效率为98.38%，两组比较（P＜0.05），差异有统计学意义。结论醒脑静联合果糖、纳洛酮具有协同作用，可提高急性重度酒精中毒患者的恢复质量，缩短苏醒时间，减少继发损害。
목적：관찰성뇌정연합과당、납락동재치료급성중도주정중독중적효과。방법선택아원2013년9월～2014년9월123례급성중도주정중독환자，근거수치순위분위량조：단수61례환자위대조조，급여납락동+생리염수연합치료，쌍수62례환자재대조조기출상가용성뇌정주사액，병장납락동조적용제생리염수개위과당주사액，관찰량조구치효과。결과관찰조공제실조기환자회복청성시간화증상소실시간분별위（74.8±20.4）min、（264.5±50.6）min，혼수기환자회복청성시간화증상소실시간분별위（153.4±36.7）min、（420.7±102.8）min，균단우대조조，급구총유효솔위98.38%，량조비교（P＜0.05），차이유통계학의의。결론성뇌정연합과당、납락동구유협동작용，가제고급성중도주정중독환자적회복질량，축단소성시간，감소계발손해。
Objective Xingnaojing joint observation fructose, the effect of naloxone in the treat-ment of acute severe alcoholism.Methods Our hospital in September 2013 September 2014 123 patients with severe cases of acute alcoholism, according to rank admitted into two groups: 61 pa-tients in the singular as a control group given saline+naloxone combination therapy, double the number 62 patients in the control group, based on the use XNJI, solvent saline and naloxone group to fructose injection, treatment effects were observed.Results Ataxia patients in the obser-vation group recovery time and awake time symptoms were (74.8±20.4)min, (264.5±50.6)min, co-matose patients recovery time and symptoms awake time was (153.4 ±36.7)min, (420.7 ±102.8)min,were shorter than the control group, the total effective rate of 98.38% first aid, the two groups P<0.05, significant difference. Conclusions Xingnaojing joint fructose, naloxone had a synergistic effect, can improve the quality of recovery in patients with acute severe alcoholism, shorten recov-ery time, reduced secondary damage.