IL-33在类风湿关节炎发病机制中的研究进展
IL-33재류풍습관절염발병궤제중적연구진전
Advances on the Pathological Roles of IL-33 in RA
  • 万方数据
    医学信息 의학신식
    MEDICAL INFORMATION
    2015年 15期 347-347,348 ,共2页

    穆思婕%于泓%樊佳佳

    목사첩%우홍%번가가

    类风湿性关节炎%IL-33/IL-33R%自身免疫性疾病 類風濕性關節炎%IL-33/IL-33R%自身免疫性疾病
    류풍습성관절염%IL-33/IL-33R%자신면역성질병
    Rheumatoid arthritis%IL-33/IL-33R%Autoimmune disease
    白细胞介素33(IL-33)是IL-1家族的一个新的细胞因子。研究发现，IL-33因其促炎作用而在实验性炎症关节炎和人类风湿性关节炎的疾病过程中起重要作用。本文重在综述IL-33的生物学特点，总结近年来IL-33在RA发病机制中的研究进展，讨论IL-33靶向治疗在自身免疫性疾病中的治疗前景。
    백세포개소33(IL-33)시IL-1가족적일개신적세포인자。연구발현，IL-33인기촉염작용이재실험성염증관절염화인류풍습성관절염적질병과정중기중요작용。본문중재종술IL-33적생물학특점，총결근년래IL-33재RA발병궤제중적연구진전，토론IL-33파향치료재자신면역성질병중적치료전경。
    Interleukin-3 (IL-33) , a member of the IL-1 cytokine family, was recognized to perform as an inflammatory cytokine, exerted profound ef ects in human RA and experimental in flammatory arthritis. In this review, we discuss the biological features of IL-33 and summarize recent advances on the pathological roles of IL-33 in RA and discuss the therapeutic significance of these new findings.
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