CAJ | 학술논문

眼部独特的自我保护结构使得传统的给药方式效率低下、生物利用度极低，给很多药物的临床应用带来了不少麻烦。近年来，各种新技术如纳米技术的研究和应用，使眼科药物的传递技术获得了长足发展。为此本文对眼科药物的传递系统及其近年来的研究进展与应用进行了综述。
안부독특적자아보호결구사득전통적급약방식효솔저하、생물이용도겁저，급흔다약물적림상응용대래료불소마번。근년래，각충신기술여납미기술적연구화응용，사안과약물적전체기술획득료장족발전。위차본문대안과약물적전체계통급기근년래적연구진전여응용진행료종술。
The eye is a highly protected organ , which makes it a formida-ble task to develop an effective drug delivery approach for ocular disea-ses.Transport of drugs applied by traditional dosage forms such as topical and intravitreal routes of administration is severely restricted to the eye , especially to the posterior segment areas.During the past decades , great progress has been made in ocular drug delivery systems facilitated by new technologies such as microemulsion , nanosuspension , nanoparticle , lipo-some, niosome, dendrimer, contact lens, intraocular implants, ionto-phoresis and microneedle , et al.In this review , recent developments of ocular drug delivery systems are summarized.