CAJ | 학술논문

目的：观察滋阴益气中药减少成年男性肾病综合征复发的临床疗效。方法将100例男性肾病综合征患者按入组顺序单双号随机分为观察组和对照组，各50例。观察组患者给予西医常规治疗和滋阴益气中药，对照组给予常规西医治疗。治疗12个月后，观察相关实验室指标的变化，并随访18个月，观察两组患者的复发率。结果18个月随访期结束后，观察组在各观察节点复发例数均低于对照组，总复发率为18.00%，显著低于对照组的62.00%（ P＜0.05）；治疗后，两组患者血清总蛋白( TP )、血清白蛋白( ALB )、总胆固醇( TC )、三酰甘油( TG )及24 h尿蛋白均与本组治疗前比较，差异有统计学意义（ P＜0.05），而观察组各项指标改善更明显（ P＜0.05）。结论滋阴益气中药可显著降低成年男性肾病综合征复发率，值得临床进一步研究。
목적：관찰자음익기중약감소성년남성신병종합정복발적림상료효。방법장100례남성신병종합정환자안입조순서단쌍호수궤분위관찰조화대조조，각50례。관찰조환자급여서의상규치료화자음익기중약，대조조급여상규서의치료。치료12개월후，관찰상관실험실지표적변화，병수방18개월，관찰량조환자적복발솔。결과18개월수방기결속후，관찰조재각관찰절점복발례수균저우대조조，총복발솔위18.00%，현저저우대조조적62.00%（ P＜0.05）；치료후，량조환자혈청총단백( TP )、혈청백단백( ALB )、총담고순( TC )、삼선감유( TG )급24 h뇨단백균여본조치료전비교，차이유통계학의의（ P＜0.05），이관찰조각항지표개선경명현（ P＜0.05）。결론자음익기중약가현저강저성년남성신병종합정복발솔，치득림상진일보연구。
Objective To observe the curative effect of nourishing Yin and tonifying Qi Chinese medicine for reducing the relapse of adult male nephrotic syndrome. Methods 100 adult patients male with nephrotic syndrome were randomly divided into the observation group and the control group according to the odd or even number on the enrollment,50 cases in each group. The observation group was given the routine treatment of Western medicine and traditional Chinese medicine of nourishing Yin and tonifying Qi,while the control group was given the conventional treatment of Western medicine alone. The changes of related laboratory indexes after 12-month treat-ment were observed and the two groups were followed up for 18 months for observing the recurrent rate in the two groups. Results Comparing the recurrent rate after 18-month follow up in the two groups,the recurrent cases number at each observation pitch point in the observation group was lower than that in the control group,the total recurrence rate was 18. 00%,which was significantly lower than 62. 00% in the control group( P < 0. 05);TP,ALB,TC,TG and 24 h urine protein in the two groups had statistically significantly difference between before and after treatment( P < 0. 05);but the improvement of each index in the observation group was more obvious ( P < 0. 05). Conclusion The traditional Chinese medicine of nourishing Yin and tonifying Qi can significantly reduce the recurrence rate of adult male patients with nephrotic syndrome,which is worthy of further study in clinic.