中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2015年
11期
55-58
,共4页
早产儿%呼吸窘迫综合征%宫外发育迟缓%危险因素
早產兒%呼吸窘迫綜閤徵%宮外髮育遲緩%危險因素
조산인%호흡군박종합정%궁외발육지완%위험인소
Premature infants%Respiratory distress syndrome%Extrauterine growth restriction(EUGR)%Risk factors
目的：分析早产儿发生呼吸窘迫综合征相关因素及呼吸窘迫综合征早产儿宫外发育迟缓的危险因素。方法选择呼吸窘迫综合征早产儿153例作为病例组，根据是否发生宫外发育迟缓分为EUGR组和非EUGR组，选择同期非呼吸窘迫综合征早产儿200例作为对照组，观察各组临床资料，分析相关因素。结果呼吸窘迫综合征患儿与非呼吸窘迫综合征患儿EUGR及严重EUGR发生率差异均有统计学意义(P<0.05)。胎龄、出生体重、多胎率、预防性应用PS率、产前激素应用率、宫内窘迫或窒息、羊水吸入、宫内感染、前置胎盘/胎盘早剥、剖宫产、妊娠期高血压病、妊娠期糖尿病发生率是早产儿发生呼吸窘迫综合征的相关因素(P<0.05)。胎龄<31周、多胎、达全量肠内营养时间、喂养不耐受、恢复出生体重时间是呼吸窘迫综合征早产儿EUGR独立危险因素(P<0.05)，产前激素应用是呼吸窘迫综合征早产儿EUGR保护因素(P<0.05)。结论胎龄小和多胎是早产儿发生呼吸窘迫综合征及患儿EUGR的共同危险因素，产前激素应用对两者都有一定的保护作用，呼吸窘迫综合征对患儿宫外发育有明显不良影响，呼吸窘迫综合征早产儿EUGR主要与喂养情况有关。
目的：分析早產兒髮生呼吸窘迫綜閤徵相關因素及呼吸窘迫綜閤徵早產兒宮外髮育遲緩的危險因素。方法選擇呼吸窘迫綜閤徵早產兒153例作為病例組，根據是否髮生宮外髮育遲緩分為EUGR組和非EUGR組，選擇同期非呼吸窘迫綜閤徵早產兒200例作為對照組，觀察各組臨床資料，分析相關因素。結果呼吸窘迫綜閤徵患兒與非呼吸窘迫綜閤徵患兒EUGR及嚴重EUGR髮生率差異均有統計學意義(P<0.05)。胎齡、齣生體重、多胎率、預防性應用PS率、產前激素應用率、宮內窘迫或窒息、羊水吸入、宮內感染、前置胎盤/胎盤早剝、剖宮產、妊娠期高血壓病、妊娠期糖尿病髮生率是早產兒髮生呼吸窘迫綜閤徵的相關因素(P<0.05)。胎齡<31週、多胎、達全量腸內營養時間、餵養不耐受、恢複齣生體重時間是呼吸窘迫綜閤徵早產兒EUGR獨立危險因素(P<0.05)，產前激素應用是呼吸窘迫綜閤徵早產兒EUGR保護因素(P<0.05)。結論胎齡小和多胎是早產兒髮生呼吸窘迫綜閤徵及患兒EUGR的共同危險因素，產前激素應用對兩者都有一定的保護作用，呼吸窘迫綜閤徵對患兒宮外髮育有明顯不良影響，呼吸窘迫綜閤徵早產兒EUGR主要與餵養情況有關。
목적：분석조산인발생호흡군박종합정상관인소급호흡군박종합정조산인궁외발육지완적위험인소。방법선택호흡군박종합정조산인153례작위병례조，근거시부발생궁외발육지완분위EUGR조화비EUGR조，선택동기비호흡군박종합정조산인200례작위대조조，관찰각조림상자료，분석상관인소。결과호흡군박종합정환인여비호흡군박종합정환인EUGR급엄중EUGR발생솔차이균유통계학의의(P<0.05)。태령、출생체중、다태솔、예방성응용PS솔、산전격소응용솔、궁내군박혹질식、양수흡입、궁내감염、전치태반/태반조박、부궁산、임신기고혈압병、임신기당뇨병발생솔시조산인발생호흡군박종합정적상관인소(P<0.05)。태령<31주、다태、체전량장내영양시간、위양불내수、회복출생체중시간시호흡군박종합정조산인EUGR독립위험인소(P<0.05)，산전격소응용시호흡군박종합정조산인EUGR보호인소(P<0.05)。결론태령소화다태시조산인발생호흡군박종합정급환인EUGR적공동위험인소，산전격소응용대량자도유일정적보호작용，호흡군박종합정대환인궁외발육유명현불량영향，호흡군박종합정조산인EUGR주요여위양정황유관。
Objective To analyze the relevant factors of respiratory distress syndrome for premature infants and the risk factors of extrauterine growth restriction(EUGR)for the premature infants with respiratory distress syndrome. Methods All 153 premature infants with respiratory distress syndrome were selected as case group, and they were assigned to EUGR group and non-EUGR group on the basis of whether they had EUGR. 200 premature infants without respiratory distress syndrome were selected as control group during the same period. Clinical data of each group were observed and relevant factors were analyzed. Results Differences of incidence rates of EUGR and severe EUGR between the pre-mature infants with respiratory distress syndrome and those without respiratory distress syndrome were statistically sig-nificant (P<0.05). Incidence rates of gestational age, birth weight, multiple pregnancy rate, preventive application rate of PS,antenatal application rate of hormone,fetal distress or asphyxia,amniotic fluid aspiration,intrauterine in-fection, placenta previa/placental abruption, cesarean section, pregnancy-induced hypertension and ges tational dia-betes mellitus were relevant factors of respiratory distress syndrome for premature infants (P<0.05). Gestational age of less than 31 weeks, multiple pregnancy, time reaching total enteral nutrition, feeding intolerance, and time resuming birth weight were independent risk factors of EUGR for premature patients with respiratory distress syndrome (P<0.05). Antenatal application of hormone was the protective factor of EUGR for premature infants with respiratory dis-tress syndrome (P<0.05). Conclusion Young gestational age and multiple pregnancy are common risk factors of respi-ratory distress syndrome and EUGR for premature infants, and antenatal application of hormone has protective effect on the two diseases. Respiratory distress syndrome has obvious adverse effect on infants' extrauterine growth, and EU-GR for premature infants with respiratory distress syndrome is mainly related to feeding.
