CAJ | 학술논문

目的：观察治瘀汤口服联合药渣外敷治疗气滞血瘀型子宫内膜异位症的临床疗效。方法选择辨证为气滞血瘀型子宫内膜异位症慢性盆腔疼痛的患者72例，随机分为研究组和对照组，各36例。研究组患者给予治瘀汤口服联合药渣外敷治疗，对照组给予丹莪妇康煎膏治疗，月经后第15天开始用药，2周为1个疗程，下一个月经周期继续第2个疗程。连续治疗3个疗程后，比较两组患者的慢性盆腔疼痛程度、中医证候积分、CA125指标改善情况及临床疗效。结果研究组与对照组患者慢性盆腔疼痛率分别为16.67%和44.44%，中医证候积分分别为（7.4 ± 3.2）分和（9.1±3.6）分，CA125指标分别为（24.8±4.7）U/mL和（28.3±5.5）U/mL，差异均有统计学意义（ P＜0.05）；研究组总有效率为86.11%，与对照组的72.22%比较，差异无统计学意义（ P＞0.05）。结论治瘀汤口服联合药渣外敷治疗气滞血瘀型子宫内膜异位症，可显著缓解患者慢性盆腔疼痛，改善其临床症状、降低CA125指标，疗效优于丹莪妇康煎膏。
목적：관찰치어탕구복연합약사외부치료기체혈어형자궁내막이위증적림상료효。방법선택변증위기체혈어형자궁내막이위증만성분강동통적환자72례，수궤분위연구조화대조조，각36례。연구조환자급여치어탕구복연합약사외부치료，대조조급여단아부강전고치료，월경후제15천개시용약，2주위1개료정，하일개월경주기계속제2개료정。련속치료3개료정후，비교량조환자적만성분강동통정도、중의증후적분、CA125지표개선정황급림상료효。결과연구조여대조조환자만성분강동통솔분별위16.67%화44.44%，중의증후적분분별위（7.4 ± 3.2）분화（9.1±3.6）분，CA125지표분별위（24.8±4.7）U/mL화（28.3±5.5）U/mL，차이균유통계학의의（ P＜0.05）；연구조총유효솔위86.11%，여대조조적72.22%비교，차이무통계학의의（ P＞0.05）。결론치어탕구복연합약사외부치료기체혈어형자궁내막이위증，가현저완해환자만성분강동통，개선기림상증상、강저CA125지표，료효우우단아부강전고。
Objective To observe the clinical efficacy of Zhiyu Decoction combined with external application of medicine dregs in treating endometriosis with the type of Qi stagnation and blood stasis. Methods Totally 72 patients with the type of Qi stagnation and blood stasis of endometriosis complicating chronic pelvic pain were and randomLy divided into the study group and the control group,36 cases in each group. The patients in the study group were given oral Zhiyu Decontion combined with the external application of medicine dregs,while the control group was given the therapy of Dane Fukang Paste. The medication was begun on 15 d after menstruation and 2 weeks were taken as 1 course of treatment. The second course of treatment was continued on the next menstrual cycle. The chronic pelvic pain degree,tradi-tional Chinese medicine(TCM) symptom scores,CA125 improvement situation after 3 continuous courses were compared between the 2 groups. Results The chronic pelvic pain rate after 3 courses of treatment in the study group and the control group were 16. 67% and 44. 44% respectively,the TCM syndrome integral scores were(7. 4 ± 3. 2)points and(9. 1 ± 3. 6)points respectively,CA125 was(24. 8+4. 7)U/mL and(28. 3+5. 5)U/mL respectively,the differences between the two groups were statistically significant( P < 0. 05);the total effective rates of the study group and the control group were 86. 11% and 72. 22% respectively,showing no statistical differences between the two groups( P > 0. 05). Conclusion Zhiyu Decoction combined with the external application of medicine dregs in the treatment of the type of Qi stagnation and blood stasis of endometriosis can obviously alleviate the chronic pelvic pain,improve the clinical symptoms and decrease the CA125 index,its curative effect is superior to that of Dane Fukang Paste.